Detalhe da pesquisa
1.
CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides.
Nat Immunol
; 24(12): 2121-2134, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37945821
2.
Notch and the pre-TCR coordinate thymocyte proliferation by induction of the SCF subunits Fbxl1 and Fbxl12.
Nat Immunol
; 20(10): 1381-1392, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31451788
3.
Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides.
Nat Immunol
; 25(3): 579, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38057618
4.
THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.
Nat Immunol
; 18(4): 433-441, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28250424
5.
Themis2 lowers the threshold for B cell activation during positive selection.
Nat Immunol
; 18(2): 205-213, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27992403
6.
LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.
Nat Immunol
; 16(9): 980-90, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26214741
7.
A ThPOK-LRF transcriptional node maintains the integrity and effector potential of post-thymic CD4+ T cells.
Nat Immunol
; 15(10): 947-56, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25129370
8.
Erratum: THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1.
Nat Immunol
; 18(6): 705, 2017 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28518157
9.
New insights into TCR ß-selection.
Trends Immunol
; 42(8): 735-750, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34261578
10.
CD5 helps aspiring regulatory T cells ward off unwelcome cytokine advances.
Immunity
; 42(3): 395-6, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25786168
11.
Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells.
Nat Immunol
; 12(2): 129-36, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21186366
12.
CD5 dynamically calibrates basal NF-κB signaling in T cells during thymic development and peripheral activation.
Proc Natl Acad Sci U S A
; 117(25): 14342-14353, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513716
13.
CD5 signalosome coordinates antagonist TCR signals to control the generation of Treg cells induced by foreign antigens.
Proc Natl Acad Sci U S A
; 117(23): 12969-12979, 2020 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32434911
14.
Ldb1 is required for Lmo2 oncogene-induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia.
Blood
; 135(25): 2252-2265, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32181817
15.
SOCS3 is a suppressor of γc cytokine signaling and constrains generation of murine Foxp3+ regulatory T cells.
Eur J Immunol
; 50(7): 986-999, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144749
16.
Themis, a T cell-specific protein important for late thymocyte development.
Nat Immunol
; 10(8): 840-7, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19597498
17.
THEMIS: Two Models, Different Thresholds.
Trends Immunol
; 38(9): 622-632, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28697966
18.
Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.
Proc Natl Acad Sci U S A
; 113(8): E1016-25, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26862168
19.
Ldb1 complexes: the new master regulators of erythroid gene transcription.
Trends Genet
; 30(1): 1-9, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24290192
20.
Chromosome choice for initiation of V-(D)-J recombination is not governed by genomic imprinting.
Immunol Cell Biol
; 95(5): 473-477, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28244489