Detalhe da pesquisa
1.
P-Rex1 and P-Rex2 RacGEFs and cancer.
Biochem Soc Trans
; 45(4): 963-77, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28710285
2.
The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.
J Biol Chem
; 290(34): 20827-20840, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26112412
3.
Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism.
Nat Struct Mol Biol
; 29(8): 767-773, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35864164
4.
Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1.
Sci Signal
; 14(681)2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33947796
5.
Cell-targeted PD-1 agonists that mimic PD-L1 are potent T cell inhibitors.
JCI Insight
; 6(20)2021 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34491911
6.
Amyloidogenicity at a Distance: How Distal Protein Regions Modulate Aggregation in Disease.
J Mol Biol
; 429(9): 1289-1304, 2017 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28342736