Detalhe da pesquisa
1.
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity.
Cell Mol Life Sci
; 81(1): 102, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38409522
2.
Gene-expression profiling of laser-dissected islets and studies in deficient mice reveal chemokines as differential driving force of type 1 diabetes.
J Autoimmun
; 143: 103161, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38141419
3.
A structural model of the iRhom-ADAM17 sheddase complex reveals functional insights into its trafficking and activity.
Cell Mol Life Sci
; 80(5): 135, 2023 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37119365
4.
Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone.
Proc Natl Acad Sci U S A
; 118(38)2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34526403
5.
The collectrin-like part of the SARS-CoV-1 and -2 receptor ACE2 is shed by the metalloproteinases ADAM10 and ADAM17.
FASEB J
; 36(3): e22234, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199397
6.
Adjusting the water-sensitivity of sugar/boronate-based organogels.
Soft Matter
; 18(47): 9026-9036, 2022 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36408633
7.
The metalloproteinase ADAM10 requires its activity to sustain surface expression.
Cell Mol Life Sci
; 78(2): 715-732, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32372373
8.
The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
Cell Mol Life Sci
; 78(11): 5015-5040, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33950315
9.
Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells.
J Cell Mol Med
; 25(4): 1982-1999, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33314720
10.
The role of resistance to inhibitors of cholinesterase 8b in the control of heart rate.
Physiol Genomics
; 53(4): 150-159, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33719582
11.
Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro.
Mediators Inflamm
; 2021: 6665028, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33814981
12.
Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.
Hum Mol Genet
; 27(9): 1533-1544, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29452352
13.
Impairment of carbonic anhydrase IX ectodomain cleavage reinforces tumorigenic and metastatic phenotype of cancer cells.
Br J Cancer
; 122(11): 1590-1603, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32210366
14.
Boron Effect on Sugar-Based Organogelators.
Chemistry
; 26(61): 13927-13934, 2020 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32579731
15.
The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System.
Cereb Cortex
; 29(5): 2291-2304, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30877792
16.
Strategies for Neuroprotection in Multiple Sclerosis and the Role of Calcium.
Int J Mol Sci
; 21(5)2020 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32121306
17.
The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner.
Int J Mol Sci
; 21(17)2020 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32825187
18.
The metalloproteinase ADAM15 is upregulated by shear stress and promotes survival of endothelial cells.
J Mol Cell Cardiol
; 134: 51-61, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31271758
19.
ATP-sensitive potassium channels in the sinoatrial node contribute to heart rate control and adaptation to hypoxia.
J Biol Chem
; 293(23): 8912-8921, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29666184
20.
Amphiregulin Regulates Phagocytosis-Induced Cell Death in Monocytes via EGFR and the Bcl-2 Protein Family.
Mediators Inflamm
; 2019: 1603131, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32082070