Detalhe da pesquisa
1.
Epetraborole, a leucyl-tRNA synthetase inhibitor, demonstrates murine efficacy, enhancing the in vivo activity of ceftazidime against Burkholderia pseudomallei, the causative agent of melioidosis.
PLoS Negl Trop Dis
; 17(11): e0011795, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-38011278
2.
Further insights into the mode of action of the lipoglycopeptide telavancin through global gene expression studies.
Antimicrob Agents Chemother
; 56(6): 3157-64, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22411615
3.
Fluorescence microscopy demonstrates enhanced targeting of telavancin to the division septum of Staphylococcus aureus.
Antimicrob Agents Chemother
; 54(5): 2198-200, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20176907
4.
In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis.
PLoS Negl Trop Dis
; 14(1): e0007957, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31986143
5.
Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 2. Ketone Linked Analogs.
ACS Infect Dis
; 6(2): 180-185, 2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31876143
6.
Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs.
ACS Infect Dis
; 6(2): 173-179, 2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31876154
7.
Telavancin disrupts the functional integrity of the bacterial membrane through targeted interaction with the cell wall precursor lipid II.
Antimicrob Agents Chemother
; 53(8): 3375-83, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19470513
8.
Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis.
Nat Commun
; 10(1): 2816, 2019 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31249291
9.
Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.
J Med Chem
; 62(5): 2521-2540, 2019 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30730745
10.
Modes of antifungal action of (2E)-alkenals against Saccharomyces cerevisiae.
J Agric Food Chem
; 51(14): 3951-7, 2003 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12822929
11.
Studies on the mechanism of telavancin decreased susceptibility in a laboratory-derived mutant.
Microb Drug Resist
; 19(4): 247-55, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23551248
12.
Deprotonation of D96 in bacteriorhodopsin opens the proton uptake pathway.
Structure
; 21(2): 290-7, 2013 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23394942
13.
In vitro activity of telavancin and occurrence of vancomycin heteroresistance in isolates from patients enrolled in phase 3 clinical trials of hospital-acquired pneumonia.
Diagn Microbiol Infect Dis
; 74(4): 429-31, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23083812
14.
Membrane-protein stability in a phospholipid-based crystallization medium.
J Struct Biol
; 154(3): 223-31, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16600634
15.
Specificity of anion binding in the substrate pocket of bacteriorhodopsin.
Biochemistry
; 43(17): 4934-43, 2004 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15109251
16.
Crystallization of membrane proteins from media composed of connected-bilayer gels.
Biopolymers
; 66(5): 300-16, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12539259