Detalhe da pesquisa
1.
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Bioorg Med Chem Lett
; 20(1): 141-4, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20004571
2.
Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli.
Biochem J
; 412(1): 113-21, 2008 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18260824
3.
The role of lysine residues 297 and 306 in nucleoside triphosphate regulation of E. coli CTP synthase: inactivation by 2',3'-dialdehyde ATP and mutational analyses.
Biochim Biophys Acta
; 1764(2): 199-210, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16427816
4.
Inhibition of E. coli CTP synthase by the "positive" allosteric effector GTP.
Biochim Biophys Acta
; 1699(1-2): 213-20, 2004 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15158730
5.
Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax.
J Biol Chem
; 283(4): 2010-20, 2008 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18003612
6.
Alternative substrates for wild-type and L109A E. coli CTP synthases: kinetic evidence for a constricted ammonia tunnel.
Eur J Biochem
; 271(21): 4204-12, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15511226
7.
Limited proteolysis of Escherichia coli cytidine 5'-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis.
Eur J Biochem
; 270(10): 2195-206, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12752439
8.
Ground state, intermediate, and multivalent nucleotide analogue inhibitors of cytidine 5'-triphosphate synthase.
ChemMedChem
; 3(12): 1853-7, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18988211