Detalhe da pesquisa
1.
PCSK9 ablation attenuates Aß pathology, neuroinflammation and cognitive dysfunctions in 5XFAD mice.
Brain Behav Immun
; 115: 517-534, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37967665
2.
Gene Silencing of Angiopoietin-like 3 (ANGPTL3) Induced De Novo Lipogenesis and Lipid Accumulation in Huh7 Cell Line.
Int J Mol Sci
; 25(7)2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38612519
3.
Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9.
Pharmacol Res
; 184: 106439, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36100012
4.
Serum Levels of PCSK9 Are Increased in Patients With Active Ulcerative Colitis Representing a Potential Biomarker of Disease Activity: A Cross-sectional Study.
J Clin Gastroenterol
; 56(9): 787-793, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34560758
5.
Cytotoxicity of Alizarine versus Tetrabromocathecol Cyclometalated Pt(II) Theranostic Agents: A Combined Experimental and Computational Investigation.
Inorg Chem
; 61(18): 7188-7200, 2022 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35467854
6.
HDL Cholesterol Efflux and Serum Cholesterol Loading Capacity Alterations Associate to Macrophage Cholesterol Accumulation in FH Patients with Achilles Tendon Xanthoma.
Int J Mol Sci
; 23(15)2022 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35897824
7.
PCSK9 Affects Astrocyte Cholesterol Metabolism and Reduces Neuron Cholesterol Supplying In Vitro: Potential Implications in Alzheimer's Disease.
Int J Mol Sci
; 23(20)2022 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36293049
8.
NMR, LC-MS Characterization of Rydingia michauxii Extracts, Identification of Natural Products Acting as Modulators of LDLR and PCSK9.
Molecules
; 27(7)2022 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35408655
9.
Leptin, Resistin, and Proprotein Convertase Subtilisin/Kexin Type 9: The Role of STAT3.
Am J Pathol
; 190(11): 2226-2236, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32798443
10.
PCSK9 Induces Rat Smooth Muscle Cell Proliferation and Counteracts the Pleiotropic Effects of Simvastatin.
Int J Mol Sci
; 22(8)2021 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923431
11.
The Modulation of PCSK9 and LDLR by Supercritical CO2 Extracts of Mentha longifolia and Isolated Piperitone Oxide, an In Vitro Study.
Molecules
; 26(13)2021 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34202378
12.
Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: New therapeutic approaches for the treatment of atherogenic dyslipidemia.
Pharmacol Res
; 153: 104653, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31931117
13.
Current Evidence and Future Perspectives on Pharmacological Treatment of Calcific Aortic Valve Stenosis.
Int J Mol Sci
; 21(21)2020 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33158204
14.
Plasma PCSK9 levels and lipoprotein distribution are preserved in carriers of genetic HDL disorders.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1863(9): 991-997, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29852278
15.
Peptide modulators of Rac1/Tiam1 protein-protein interaction: An alternative approach for cardiovascular diseases.
Biopolymers
; 2017 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29178143
16.
Geranylgeraniol prevents the simvastatin-induced PCSK9 expression: Role of the small G protein Rac1.
Pharmacol Res
; 122: 96-104, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28554582
17.
Identification of 4-amino-2-Pyridones as new potent PCSK9 inhibitors: From phenotypic hit discovery to in vivo tolerability.
Eur J Med Chem
; 265: 116063, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38160616
18.
Cytotoxic Pt(II) complexes containing alizarin: a selective carrier for DNA metalation.
Dalton Trans
; 53(6): 2602-2618, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38223973
19.
Legacy perfluoro-alkyl substances impair LDL-cholesterol uptake independently from PCSK9-function.
Toxicol Rep
; 11: 288-294, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37818225
20.
Effects of Handroanthus impetiginosus (Mart. ex DC.) Mattos extract on inflammatory, immune, atherogenic profile and differentiation in THP-1 cell line.
Nat Prod Res
; : 1-6, 2023 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37548308