Detalhe da pesquisa
1.
Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies.
Proc Natl Acad Sci U S A
; 120(31): e2300895120, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487077
2.
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies.
Proc Natl Acad Sci U S A
; 119(36): e2205983119, 2022 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36037341
3.
CD8+ T cell priming that is required for curative intratumorally anchored anti-4-1BB immunotherapy is constrained by Tregs.
Nat Commun
; 15(1): 1900, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38429261
4.
Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy.
bioRxiv
; 2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36778460
5.
Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells.
ACS Cent Sci
; 9(9): 1835-1845, 2023 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37780364
6.
An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy.
MAbs
; 14(1): 2088454, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924382
7.
Intratumoral nanobody-IL-2 fusions that bind the tumor extracellular matrix suppress solid tumor growth in mice.
PNAS Nexus
; 1(5): pgac244, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36712341
8.
Maximizing response to intratumoral immunotherapy in mice by tuning local retention.
Nat Commun
; 13(1): 109, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013154
9.
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity.
Nat Biomed Eng
; 6(2): 129-143, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013574
10.
Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy.
Sci Transl Med
; 11(498)2019 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31243150