Detalhe da pesquisa
1.
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives.
Int J Mol Sci
; 25(2)2024 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279210
2.
Terpene-Containing Analogues of Glitazars as Potential Therapeutic Agents for Metabolic Syndrome.
Curr Issues Mol Biol
; 45(3): 2230-2247, 2023 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36975514
3.
Natural Products and Their Derivatives as Inhibitors of the DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1.
Int J Mol Sci
; 24(6)2023 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982848
4.
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties.
Int J Mol Sci
; 24(4)2023 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36835244
5.
Synthesis and Evaluation of Hypoglycemic Activity of Structural Isomers of ((Benzyloxy)phenyl)propanoic Acid Bearing an Aminobornyl Moiety.
Int J Mol Sci
; 24(9)2023 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175725
6.
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor.
Int J Mol Sci
; 24(6)2023 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982223
7.
Monoterpene substituted thiazolidin-4-ones as novel TDP1 inhibitors: Synthesis, biological evaluation and docking.
Bioorg Med Chem Lett
; 73: 128909, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907608
8.
Study of Hypoglycemic Activity of Novel 9-N-alkyltetrahydroberberine Derivatives.
Int J Mol Sci
; 23(22)2022 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430664
9.
Carbonylation of Polyfluorinated 1-Arylalkan-1-ols and Diols in Superacids.
Molecules
; 27(24)2022 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36557890
10.
Triterpenic Acid Amides as Potential Inhibitors of the SARS-CoV-2 Main Protease.
Molecules
; 28(1)2022 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36615498
11.
New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1.
Int J Mol Sci
; 22(21)2021 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34768766
12.
Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors.
Molecules
; 26(7)2021 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33808389
13.
Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40).
Bioorg Chem
; 99: 103830, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32289588
14.
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.
Int J Mol Sci
; 21(19)2020 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998385
15.
New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors.
Molecules
; 24(20)2019 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31619021
16.
Novel derivatives of usnic acid effectively inhibiting reproduction of influenza A virus.
Bioorg Med Chem
; 22(24): 6826-36, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25464881
17.
The Potential of Usnic-Acid-Based Thiazolo-Thiophenes as Inhibitors of the Main Protease of SARS-CoV-2 Viruses.
Viruses
; 16(2)2024 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38399993
18.
Bornyl-Containing Derivatives of Benzyloxyphenylpropanoic Acid as FFAR1 Agonists: In Vitro and In Vivo Studies.
Pharmaceutics
; 15(6)2023 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37376118
19.
Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan.
J Pharm Biomed Anal
; 236: 115731, 2023 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37741072
20.
Usnic Acid Derivatives Inhibit DNA Repair Enzymes Tyrosyl-DNA Phosphodiesterases 1 and 2 and Act as Potential Anticancer Agents.
Genes (Basel)
; 14(10)2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37895279