Detalhe da pesquisa
1.
Antineoplastic effects of pharmacological inhibitors of aurora kinases in CSF3RT618I-driven cells.
Blood Cells Mol Dis
; 104: 102799, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37839173
2.
Pharmacological Inhibition of PIP4K2 Potentiates Venetoclax-Induced Apoptosis in Acute Myeloid Leukemia.
Int J Mol Sci
; 24(23)2023 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38069220
3.
Suppression of multiple anti-apoptotic BCL2 family proteins recapitulates the effects of JAK2 inhibitors in JAK2V617F driven myeloproliferative neoplasms.
Cancer Sci
; 113(2): 597-608, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34808021
4.
NSC305787, a pharmacological ezrin inhibitor, exhibits antineoplastic activity in pancreatic cancer cells.
Invest New Drugs
; 40(4): 728-737, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35477813
5.
Phenformin increases early hematopoietic progenitors in the Jak2V617F murine model.
Invest New Drugs
; 40(3): 576-585, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35015172
6.
STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells.
Invest New Drugs
; 40(2): 438-452, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34837603
7.
AD80, a multikinase inhibitor, exhibits antineoplastic effects in acute leukemia cellular models targeting the PI3K/STMN1 axis.
Invest New Drugs
; 39(4): 1139-1149, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33475938
8.
NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia.
Invest New Drugs
; 39(3): 736-746, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33403501
9.
Microemulsion for Prolonged Release of Fenretinide in the Mammary Tissue and Prevention of Breast Cancer Development.
Mol Pharm
; 18(9): 3401-3417, 2021 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34482696
10.
Seriniquinones as Therapeutic Leads for Treatment of BRAF and NRAS Mutant Melanomas.
Molecules
; 26(23)2021 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34885944
11.
Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2V617F cells.
Invest New Drugs
; 38(3): 733-745, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31286322
12.
Stathmin 1 is highly expressed and associated with survival outcome in malignant adrenocortical tumours.
Invest New Drugs
; 38(3): 899-908, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31441020
13.
Up-regulation of SPINT2/HAI-2 by Azacytidine in bone marrow mesenchymal stromal cells affects leukemic stem cell survival and adhesion.
J Cell Mol Med
; 23(2): 1562-1571, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484958
14.
The U2AF homology motif kinase 1 (UHMK1) is upregulated upon hematopoietic cell differentiation.
Biochim Biophys Acta Mol Basis Dis
; 1864(3): 959-966, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29307747
15.
IRS1/ß-Catenin Axis Is Activated and Induces MYC Expression in Acute Lymphoblastic Leukemia Cells.
J Cell Biochem
; 118(7): 1774-1781, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27987331
16.
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway.
Biochim Biophys Acta Mol Basis Dis
; 1863(2): 450-461, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27840303
17.
ANKHD1 silencing inhibits Stathmin 1 activity, cell proliferation and migration of leukemia cells.
Biochim Biophys Acta
; 1853(3): 583-93, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25523139
18.
Differential profile of PIP4K2A expression in hematological malignancies.
Blood Cells Mol Dis
; 55(3): 228-35, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26227852
19.
Ten-eleven-translocation 2 (TET2) is downregulated in myelodysplastic syndromes.
Eur J Haematol
; 94(5): 413-8, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25200248
20.
ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells.
Exp Cell Res
; 324(2): 137-45, 2014 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24726915