[Hemodynamic status in liver cirrhosis with portal hypertension: a retrospective study on 49 patients]. / Assetto emodinamico nella cirrosi epatica con ipertensione portale: studio retrospettivo su 49 pazienti.

The Authors report on the data obtained and their evaluation by means of analysis of seven variables and four indices, in 49 cirrhotic patients with portal hypertension and in 10 control patients. Haemodynamic analysis offers the possibility of identifying the dynamic transition stages of a response to stress showing varying degrees of compensation and establishing categories of patients on the basis of cardiovascular and metabolic parameters in relation to liver damage. The Authors, according to Siegel studies, retain that this is a valid method which enables us to obtain useful information on the haemodynamic status of the cirrhotic patient with portal hypertension.

Presence of duodenopancreatic feedback in minipigs and possible interference from the bile.

In two minipigs chronic pancreatic and duodenal fistulas, which allowed the diversion and the intestinal replacement of pancreatic secretion, were prepared. In a third minipig a chronic biliary fistula was also prepared so the bile secretion could be fed back into the intestine through a duodenal catheter. In these animals a chronic gastric fistula was made so gastric secretion could also be collected. Diversion-replacement of pure pancreatic juice and of bile were carried out in the fasting state. This study confirms the presence of a feedback regulatory mechanism in exocrine pancreatic secretion in the pig. Moreover, it suggests that bile can interfere with this phenomenon.