Detalhe da pesquisa
1.
A novel in vitro high-content imaging assay for the prediction of drug-induced lung toxicity.
Arch Toxicol
; 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38806719
2.
Retrospective analysis of the potential use of virtual control groups in preclinical toxicity assessment using the eTOX database.
Regul Toxicol Pharmacol
; 138: 105309, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36481280
3.
Statistical analysis of preclinical inter-species concordance of histopathological findings in the eTOX database.
Regul Toxicol Pharmacol
; 138: 105308, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36481279
4.
Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging.
Anal Chem
; 94(3): 1795-1803, 2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35005896
5.
Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment.
Arch Toxicol
; 96(2): 613-624, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34973110
6.
Evaluation of UV-C Decontamination of Clinical Tissue Sections for Spatially Resolved Analysis by Mass Spectrometry Imaging (MSI).
Anal Chem
; 93(5): 2767-2775, 2021 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33474935
7.
Deep Learning-Based Annotation Transfer between Molecular Imaging Modalities: An Automated Workflow for Multimodal Data Integration.
Anal Chem
; 93(6): 3061-3071, 2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33534548
8.
Method to Investigate the Distribution of Water-Soluble Drug-Delivery Systems in Fresh Frozen Tissues Using Imaging Mass Cytometry.
Anal Chem
; 93(8): 3742-3749, 2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33606520
9.
Universal Sample Preparation Unlocking Multimodal Molecular Tissue Imaging.
Anal Chem
; 92(16): 11080-11088, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32519547
10.
Mycoplasma hyopneumoniae evades phagocytic uptake by porcine alveolar macrophages in vitro.
Vet Res
; 50(1): 51, 2019 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31234931
11.
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.
Clin Cancer Res
; 30(7): 1338-1351, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37967136
12.
Metabolism-driven in vitro/in vivo disconnect of an oral ERÉ VHL-PROTAC.
Commun Biol
; 7(1): 563, 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38740899
13.
Development of a self-replicating plasmid system for Mycoplasma hyopneumoniae.
Vet Res
; 44: 63, 2013 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23895236
14.
Transposon mutagenesis in Mycoplasma hyopneumoniae using a novel mariner-based system for generating random mutations.
Vet Res
; 44: 124, 2013 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24359443
15.
Optimal experimental design for efficient toxicity testing in microphysiological systems: A bone marrow application.
Front Pharmacol
; 14: 1142581, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37063297
16.
Targeted Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution, Toxicity, and Tissue Classification Studies.
Metabolites
; 13(3)2023 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36984817
17.
The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance.
Cancer Res
; 83(23): 3989-4004, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37725704
18.
Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies.
Metabolites
; 12(3)2022 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35323705
19.
Evaluation of Formalin-Fixed and FFPE Tissues for Spatially Resolved Metabolomics and Drug Distribution Studies.
Pharmaceuticals (Basel)
; 15(11)2022 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36355479
20.
Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper.
Clin Cancer Res
; 28(21): 4724-4736, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35929986