Detalhe da pesquisa
1.
Endothelin-1 is increased in the plasma of patients hospitalised with Covid-19.
J Mol Cell Cardiol
; 167: 92-96, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35339512
2.
Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation.
Immunity
; 38(2): 285-95, 2013 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23395675
3.
Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention.
J Interv Cardiol
; 2022: 9154048, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36262459
4.
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.
Br J Clin Pharmacol
; 88(12): 5295-5306, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35748053
5.
International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand.
Pharmacol Rev
; 71(4): 467-502, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492821
6.
Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction.
Eur Heart J
; 41(34): 3239-3252, 2020 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31972008
7.
8.
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension.
Circulation
; 135(12): 1160-1173, 2017 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137936
9.
Genes encoding ACE2, TMPRSS2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes.
J Mol Cell Cardiol
; 147: 88-91, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818486
10.
Expression of the apelin receptor, a novel potential therapeutic target, and its endogenous ligands in diverse stem cell populations in human glioblastoma.
Front Neurosci
; 18: 1379658, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38803685
11.
The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan.
Front Pharmacol
; 15: 1369489, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38655187
12.
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.
Biosci Rep
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38747277
13.
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.
Nat Med
; 12(9): 1075-80, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16892061
14.
International Union of Basic and Clinical Pharmacology. LXXVII. Kisspeptin receptor nomenclature, distribution, and function.
Pharmacol Rev
; 62(4): 565-78, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21079036
15.
International Union of Basic and Clinical Pharmacology. LXXIV. Apelin receptor nomenclature, distribution, pharmacology, and function.
Pharmacol Rev
; 62(3): 331-42, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20605969
16.
Targeting the apelin system for the treatment of cardiovascular diseases.
Cardiovasc Res
; 119(17): 2683-2696, 2023 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37956047
17.
Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands.
Front Endocrinol (Lausanne)
; 14: 1139121, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36967803
18.
Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes.
Cardiovasc Res
; 119(2): 587-598, 2023 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239923
19.
International Union of Pharmacology. LXXII. Recommendations for trace amine receptor nomenclature.
Pharmacol Rev
; 61(1): 1-8, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19325074
20.
The therapeutic potential of apelin in kidney disease.
Nat Rev Nephrol
; 17(12): 840-853, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34389827