Detalhe da pesquisa
1.
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Cell
; 186(4): 786-802.e28, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754049
2.
Genetic and pharmacological PARP inhibition reduces axonal degeneration in C. elegans models of ALS.
Hum Mol Genet
; 31(19): 3313-3324, 2022 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594544
3.
Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects.
Proc Natl Acad Sci U S A
; 118(25)2021 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140407
4.
Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo.
Neurobiol Dis
; 55: 64-75, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23567652
5.
Small Molecule Rescue of ATXN3 Toxicity in C. elegans via TFEB/HLH-30.
Neurotherapeutics
; 18(2): 1151-1165, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33782863
6.
A single copy transgenic mutant FUS strain reproduces age-dependent ALS phenotypes in C. elegans.
MicroPubl Biol
; 20212021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34568776
7.
Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditiselegans model of spinal muscular atrophy.
Dis Model Mech
; 13(12)2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106327
8.
RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement.
Mol Ther Nucleic Acids
; 15: 12-25, 2019 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30831428
9.
The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis.
Neurotherapeutics
; 16(4): 1149-1166, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31342410
10.
Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.
JCI Insight
; 2(22)2017 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29202456
11.
Correction to: The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis.
Neurotherapeutics
; 18(3): 2128, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34100189
12.
Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.
PLoS One
; 7(7): e42117, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22848727
13.
De novo truncating mutation in Kinesin 17 associated with schizophrenia.
Biol Psychiatry
; 68(7): 649-56, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20646681