Detalhe da pesquisa
1.
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity.
Proc Natl Acad Sci U S A
; 119(15): e2109617119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35353605
2.
Uncovering a neurological protein signature for severe COVID-19.
Neurobiol Dis
; 182: 106147, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37178811
3.
Cerebrospinal α-Synuclein Oligomers Reflect Disease Motor Severity in DeNoPa Longitudinal Cohort.
Mov Disord
; 36(9): 2048-2056, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33978256
4.
CSF or serum neurofilament light added to α-Synuclein panel discriminates Parkinson's from controls.
Mov Disord
; 35(2): 288-295, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31737952
5.
Retraction Notice to: Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders.
Mol Ther
; 2024 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38608700
6.
Retraction Notice to: Corrigendum to "Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders".
Mol Ther
; 2024 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38608701
7.
CSF Biomarkers Reflecting Protein Pathology and Axonal Degeneration Are Associated with Memory, Attentional, and Executive Functioning in Early-Stage Parkinson's Disease.
Int J Mol Sci
; 21(22)2020 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33198266
8.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 129, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716614
9.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 169, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843738
10.
α-Synuclein species as potential cerebrospinal fluid biomarkers for dementia with lewy bodies.
Mov Disord
; 33(11): 1724-1733, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30440090
11.
Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects.
J Neural Transm (Vienna)
; 124(6): 721-738, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28477284
12.
Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice.
Brain
; 139(Pt 3): 856-70, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26719384
13.
Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders.
Mol Ther
; 24(4): 746-58, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26700614
14.
Longitudinal changes in CSF alpha-synuclein species reflect Parkinson's disease progression.
Mov Disord
; 31(10): 1535-1542, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27548849
15.
Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.
Neurobiol Dis
; 78: 100-14, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25818009
16.
Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.
Neurobiol Dis
; 79: 81-99, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937088
17.
Novel engineered nanobodies specific for N-terminal region of alpha-synuclein recognize Lewy-body pathology and inhibit in-vitro seeded aggregation and toxicity.
FEBS J
; 289(15): 4657-4673, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35090199
18.
Cerebrospinal Fluid α-Synuclein Species in Cognitive and Movements Disorders.
Brain Sci
; 11(1)2021 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33477387
19.
Preanalytical Stability of CSF Total and Oligomeric Alpha-Synuclein.
Front Aging Neurosci
; 13: 638718, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33762924
20.
Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort.
Viruses
; 13(5)2021 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33925055