Detalhe da pesquisa
1.
Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications.
J Am Chem Soc
; 144(2): 832-844, 2022 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34985906
2.
Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on α-1,6 Mannanases.
Chemistry
; 27(37): 9519-9523, 2021 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33878235
3.
Distortion of mannoimidazole supports a B2,5 boat transition state for the family GH125 α-1,6-mannosidase from Clostridium perfringens.
Org Biomol Chem
; 17(34): 7863-7869, 2019 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31407758
4.
Computational Design of Experiment Unveils the Conformational Reaction Coordinate of GH125 α-Mannosidases.
J Am Chem Soc
; 139(3): 1085-1088, 2017 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28026180
5.
Conformational Analysis of the Mannosidase Inhibitor Kifunensine: A Quantum Mechanical and Structural Approach.
Chembiochem
; 18(15): 1496-1501, 2017 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28493500
6.
Conformational Behaviour of Azasugars Based on Mannuronic Acid.
Chembiochem
; 18(13): 1297-1304, 2017 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28256791
7.
Human O-GlcNAcase Uses a Preactivated Boat-skew Substrate Conformation for Catalysis. Evidence from X-ray Crystallography and QM/MM Metadynamics.
ACS Catal
; 13(20): 13672-13678, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37969138
8.
Trans-cyclosulfamidate mannose-configured cyclitol allows isoform-dependent inhibition of GH47 α-d-mannosidases through a bump-hole strategy.
Chem Sci
; 14(46): 13581-13586, 2023 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38033892
9.
Mannosidase mechanism: at the intersection of conformation and catalysis.
Curr Opin Struct Biol
; 62: 79-92, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31891872
10.
Structural studies of a surface-entropy reduction mutant of O-GlcNAcase.
Acta Crystallogr D Struct Biol
; 75(Pt 1): 70-78, 2019 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30644846
11.
Molecular mechanisms regulating O-linked N-acetylglucosamine (O-GlcNAc)-processing enzymes.
Curr Opin Chem Biol
; 53: 131-144, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31654859
12.
A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites.
Cell Host Microbe
; 26(3): 385-399.e9, 2019 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31513773
13.
Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms.
FEBS Lett
; 590(2): 288-97, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26823174