Detalhe da pesquisa
1.
IKKα-Mediated Noncanonical NF-κB Signaling Is Required To Support Murine Gammaherpesvirus 68 Latency In Vivo.
J Virol
; 96(10): e0002722, 2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35481781
2.
Cell migration to CXCL12 requires simultaneous IKKα and IKKß-dependent NF-κB signaling.
Biochim Biophys Acta
; 1843(9): 1796-1804, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24747690
3.
Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1ß (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.
J Biol Chem
; 288(14): 10061-10072, 2013 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23417678
4.
The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1.
J Immunol
; 188(5): 2380-6, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22287708
5.
E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.
J Biol Chem
; 287(5): 3559-72, 2012 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22158614
6.
A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.
PLoS Pathog
; 7(4): e1002026, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21533069
7.
Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation.
J Cell Biol
; 179(1): 33-40, 2007 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17923528
8.
Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected].
J Immunol
; 184(8): 4497-509, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20231695
9.
GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes.
J Biol Chem
; 285(11): 8395-407, 2010 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20048163
10.
Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.
Eur Cell Mater
; 21: 202-20, 2011 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21351054
11.
Matrix metalloproteinase 13 loss associated with impaired extracellular matrix remodeling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factors.
Arthritis Rheum
; 62(8): 2370-81, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20506238
12.
Basal and IL-1ß enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKß NF-κB activating kinases.
Sci Rep
; 11(1): 21697, 2021 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34737366
13.
Canonical NF-κB Promotes Lung Epithelial Cell Tumour Growth by Downregulating the Metastasis Suppressor CD82 and Enhancing Epithelial-to-Mesenchymal Cell Transition.
Cancers (Basel)
; 13(17)2021 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503110
14.
TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype.
J Cell Physiol
; 225(3): 682-91, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20509143
15.
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland.
J Clin Invest
; 117(12): 3988-4002, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18060036
16.
Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1.
J Cell Physiol
; 218(1): 215-27, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18803232
17.
Selective ablation of Notch3 in HCC enhances doxorubicin's death promoting effect by a p53 dependent mechanism.
J Hepatol
; 50(5): 969-79, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19304334
18.
Epigenetic Regulation of Inflammatory Cytokine-Induced Epithelial-To-Mesenchymal Cell Transition and Cancer Stem Cell Generation.
Cells
; 8(10)2019 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31557902
19.
Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy.
Ann N Y Acad Sci
; 1442(1): 17-34, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30008181
20.
CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation.
Life Sci Alliance
; 2(6)2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31792060