Detalhe da pesquisa
1.
Immunosuppression by Mutated Calreticulin Released from Malignant Cells.
Mol Cell
; 77(4): 748-760.e9, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31785928
2.
Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms.
Blood
; 141(8): 917-929, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36356299
3.
CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag.
Blood
; 138(6): 480-485, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34010413
4.
Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms.
Blood
; 138(22): 2231-2243, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34407546
5.
ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis.
Haematologica
; 108(8): 2130-2145, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36794499
6.
An inherited gain-of-function risk allele in EPOR predisposes to familial JAK2V617F myeloproliferative neoplasms.
Br J Haematol
; 198(1): 131-136, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355248
7.
Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms.
Blood
; 135(2): 133-144, 2020 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697806
8.
Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells.
Blood
; 134(26): 2383-2387, 2019 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31697834
9.
Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants.
Blood
; 133(25): 2669-2681, 2019 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30902807
10.
Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome.
Blood
; 132(12): 1318-1331, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29914977
11.
Cortical Bone Microarchitecture in Dialysis Patients.
Am J Nephrol
; 51(10): 833-838, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911468
12.
Genetic deletion of keratin 8 corrects the altered bone formation and osteopenia in a mouse model of cystic fibrosis.
Hum Mol Genet
; 25(7): 1281-93, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26769674
13.
Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis.
Blood
; 127(10): 1317-24, 2016 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26608331
14.
Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants.
Blood
; 127(10): 1325-35, 2016 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26668133
15.
New pathogenic mechanisms induced by germline erythropoietin receptor mutations in primary erythrocytosis.
Haematologica
; 103(4): 575-586, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269524
16.
Maternal embryonic leucine zipper kinase inhibitor OTSSP167 has preclinical activity in multiple myeloma bone disease.
Haematologica
; 103(8): 1359-1368, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29748441
17.
Wnt/ß-catenin signaling mediates osteoblast differentiation triggered by peptide-induced α5ß1 integrin priming in mesenchymal skeletal cells.
J Biol Chem
; 290(11): 6903-12, 2015 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631051
18.
Increased NF-κB Activity and Decreased Wnt/ß-Catenin Signaling Mediate Reduced Osteoblast Differentiation and Function in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mice.
J Biol Chem
; 290(29): 18009-18017, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26060255
19.
Not just another kinase mutation!
Blood
; 134(26): 2335-2337, 2019 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31877214
20.
Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors.
Blood
; 123(9): 1372-83, 2014 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24398328