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Int J Infect Dis ; 95: 352-360, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32205283

RESUMO

OBJECTIVES: Hoping to improve health-related effectiveness, a two-phase vaccination against rabies was designed and executed in northern Tanzania in 2018, which included geo-epidemiological and economic perspectives. METHODS: Considering the local bio-geography and attempting to rapidly establish a protective ring around a city at risk, the first phase intervened on sites surrounding that city, where the population density was lower than in the city at risk. The second phase vaccinated a rural area. RESULTS: No rabies-related case has been reported in the vaccinated areas for over a year post-immunisation; hence, the campaign is viewed as highly cost-effective. Other metrics included: rapid implementation (concluded in half the time spent on other campaigns) and the estimated cost per protected life, which was 3.28 times lower than in similar vaccinations. CONCLUSIONS: The adopted design emphasised local bio-geographical dynamics: it prevented the occurrence of an epidemic in a city with a higher demographic density than its surrounding area and it also achieved greater effectiveness than average interventions. These interdisciplinary, policy-oriented experiences have broad and immediate applications in settings of limited and/or time-sensitive (expertise, personnel, and time available to intervene) resources and conditions.


Assuntos
Programas de Imunização , Vacina Antirrábica/administração & dosagem , Raiva/prevenção & controle , Animais , Doenças do Gato/prevenção & controle , Gatos , Análise Custo-Benefício , Doenças do Cão/prevenção & controle , Cães , Feminino , Humanos , Programas de Imunização/economia , Raiva/economia , Raiva/transmissão , Vacina Antirrábica/economia , Tanzânia
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