Detalhe da pesquisa
1.
Patient-derived xenograft models of ALK+ ALCL reveal preclinical promise for therapy with brigatinib.
Br J Haematol
; 202(5): 985-994, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37357529
2.
IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma.
Blood
; 136(14): 1657-1669, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32573700
3.
Paediatric Burkitt lymphoma patient-derived xenografts capture disease characteristics over time and are a model for therapy.
Br J Haematol
; 192(2): 354-365, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32880915
4.
Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target.
Haematologica
; 106(6): 1693-1704, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32327503
5.
STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma.
Cell Rep Med
; 5(3): 101472, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38508140
6.
Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma.
Nat Commun
; 15(1): 3422, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38653965
7.
The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status.
Nat Commun
; 10(1): 5428, 2019 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31780656