Detalhe da pesquisa
1.
High-Affinity NIR-Fluorescent Inhibitors for Tumor Imaging via Carbonic Anhydrase IX.
Bioconjug Chem
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38750635
2.
Screening, Synthesis and Biochemical Characterization of SARS-CoV-2 Protease Inhibitors.
Int J Mol Sci
; 24(17)2023 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686295
3.
3-Chloro-5-Substituted-1,2,4-Thiadiazoles (TDZs) as Selective and Efficient Protein Thiol Modifiers.
Chembiochem
; 23(21): e202200417, 2022 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36066474
4.
Denaturant- or ligand-induced changes in protein volume by pressure shift assay.
Phys Chem Chem Phys
; 24(28): 17279-17288, 2022 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802138
5.
Synthesis and HDAC inhibitory activity of pyrimidine-based hydroxamic acids.
Beilstein J Org Chem
; 18: 837-844, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35923158
6.
A standard operating procedure for an enzymatic activity inhibition assay.
Eur Biophys J
; 50(3-4): 345-352, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33864100
7.
Standard operating procedure for fluorescent thermal shift assay (FTSA) for determination of protein-ligand binding and protein stability.
Eur Biophys J
; 50(3-4): 373-379, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33914114
8.
Structure and mechanism of secondary sulfonamide binding to carbonic anhydrases.
Eur Biophys J
; 50(7): 993-1011, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34328515
9.
Uncertainty in protein-ligand binding constants: asymmetric confidence intervals versus standard errors.
Eur Biophys J
; 50(3-4): 661-670, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33837826
10.
Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study.
Eur Biophys J
; 50(3-4): 411-427, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33881594
11.
Biphenyl substituted lysine derivatives as recognition elements for the matrix metalloproteinases MMP-2 and MMP-9.
Bioorg Chem
; 115: 105155, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34303036
12.
Inhibition of Carbonic Anhydrase IX Suppresses Breast Cancer Cell Motility at the Single-Cell Level.
Int J Mol Sci
; 22(21)2021 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769000
13.
Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX.
Int J Mol Sci
; 23(1)2021 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008553
14.
Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle.
Biophys J
; 119(8): 1513-1524, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32971003
15.
Thermodynamic, kinetic, and structural parameterization of human carbonic anhydrase interactions toward enhanced inhibitor design.
Q Rev Biophys
; 51: e10, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30912486
16.
Synthesis and structure-affinity relationship of chlorinated pyrrolidinone-bearing benzenesulfonamides as human carbonic anhydrase inhibitors.
Bioorg Chem
; 97: 103658, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32088419
17.
Repeatability, precision, and accuracy of the enthalpies and Gibbs energies of a protein-ligand binding reaction measured by isothermal titration calorimetry.
Eur Biophys J
; 48(2): 139-152, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30535510
18.
Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases.
Bioorg Med Chem
; 27(2): 322-337, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30553625
19.
Interaction of the middle domains stabilizes Hsp90α dimer in a closed conformation with high affinity for p23.
Biol Chem
; 399(4): 337-345, 2018 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29337688
20.
Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Eur Biophys J
; 47(3): 271-290, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28975383