Detalhe da pesquisa
1.
Sputum biomarkers during acute severe asthma attacks in children-a case-control study.
Acta Paediatr
; 111(3): 620-627, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34773288
2.
Sputum microbiomic clustering in asthma and chronic obstructive pulmonary disease reveals a Haemophilus-predominant subgroup.
Allergy
; 75(4): 808-817, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31556120
3.
Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum.
BMC Pulm Med
; 19(1): 144, 2019 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31395050
4.
Biological exacerbation clusters demonstrate asthma and chronic obstructive pulmonary disease overlap with distinct mediator and microbiome profiles.
J Allergy Clin Immunol
; 141(6): 2027-2036.e12, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29709671
5.
Moving toward endotypes in atopic dermatitis: Identification of patient clusters based on serum biomarker analysis.
J Allergy Clin Immunol
; 140(3): 730-737, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28412391
6.
Biological clustering supports both "Dutch" and "British" hypotheses of asthma and chronic obstructive pulmonary disease.
J Allergy Clin Immunol
; 135(1): 63-72, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25129678
7.
Strategies targeting the IL-4/IL-13 axes in disease.
Cytokine
; 75(1): 89-116, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26255210
8.
Development of a mouse model mimicking key aspects of a viral asthma exacerbation.
Clin Sci (Lond)
; 126(8): 567-80, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24152048
9.
Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma.
Am J Respir Crit Care Med
; 188(6): 657-63, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23590263
10.
Serum biomarker profiles suggest that atopic dermatitis is a systemic disease.
J Allergy Clin Immunol
; 141(4): 1523-1526, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29410314
11.
A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma.
Eur Respir J
; 41(2): 330-8, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22743678
12.
EASI p-EASI: Utilizing a combination of serum biomarkers offers an objective measurement tool for disease severity in atopic dermatitis patients.
J Allergy Clin Immunol
; 140(6): 1703-1705, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28823810
13.
Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction.
Sci Rep
; 13(1): 9825, 2023 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37330528
14.
IL-33, IL-25, and TSLP induce a distinct phenotypic and activation profile in human type 2 innate lymphoid cells.
Blood Adv
; 1(10): 577-589, 2017 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29296700
15.
Immunohistochemical Characterization of the IL-13:IL-4 Receptor α Axis in the Skin of Adult Patients with Moderate to Severe Atopic Dermatitis and Healthy Controls.
J Invest Dermatol
; 141(2): 440-443.e4, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32598926
16.
A predictive model of human myelotoxicity using five camptothecin derivatives and the in vitro colony-forming unit granulocyte/macrophage assay.
Clin Cancer Res
; 10(19): 6722-31, 2004 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15475463
17.
Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial.
Lancet Respir Med
; 3(9): 692-701, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26231288
18.
Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.
Nat Commun
; 6: 8327, 2015 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26365875
19.
Degradation of Quillaja saponaria Molina saponins: loss of the protective effects of a herpes simplex virus 1 subunit vaccine.
Int Immunopharmacol
; 2(12): 1703-11, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12469944
20.
A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma.
MAbs
; 6(3): 756-64, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24583620