Detalhe da pesquisa
1.
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of MHAA4549A, a Monoclonal Antibody, plus Oseltamivir in Patients Hospitalized with Severe Influenza A Virus Infection.
Antimicrob Agents Chemother
; 64(7)2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393496
2.
Pharmacokinetics and Exposure-Response Analysis of RG7667, a Combination of Two Anticytomegalovirus Monoclonal Antibodies, in a Phase 2a Randomized Trial To Prevent Cytomegalovirus Infection in High-Risk Kidney Transplant Recipients.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29133549
3.
Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of RG7667, a Combination Monoclonal Antibody, for Prevention of Cytomegalovirus Infection in High-Risk Kidney Transplant Recipients.
Antimicrob Agents Chemother
; 61(2)2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27872061
4.
Phase 2 Randomized Trial of the Safety and Efficacy of MHAA4549A, a Broadly Neutralizing Monoclonal Antibody, in a Human Influenza A Virus Challenge Model.
Antimicrob Agents Chemother
; 61(11)2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28807912
5.
Generation and Protective Ability of Influenza Virus-Specific Antibody-Dependent Cellular Cytotoxicity in Humans Elicited by Vaccination, Natural Infection, and Experimental Challenge.
J Infect Dis
; 214(6): 945-52, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27354365
6.
A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE).
Ann Rheum Dis
; 75(1): 196-202, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26038091
7.
Comprehensive profiling of the human fecal proteome from IBD patients with DIA-MS enables evaluation of disease-relevant proteins.
Proteomics Clin Appl
; : e2300075, 2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38552248
8.
Reply to Hunsberger and Memoli, "Efficacy Analysis in Healthy-Volunteer Influenza Challenge Trials: Intention To Treat".
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269431
9.
Safety and pharmacodynamics of rontalizumab in patients with systemic lupus erythematosus: results of a phase I, placebo-controlled, double-blind, dose-escalation study.
Arthritis Rheum
; 64(11): 3666-76, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22833362
10.
First-in-human phase 1 trial evaluating safety, pharmacokinetics, and pharmacodynamics of NLRP3 inflammasome inhibitor, GDC-2394, in healthy volunteers.
Clin Transl Sci
; 16(9): 1653-1666, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37350225
11.
Myeloid cell influx into the colonic epithelium is associated with disease severity and non-response to anti-Tumor Necrosis Factor Therapy in patients with Ulcerative Colitis.
bioRxiv
; 2023 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37333091
12.
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.
iScience
; 26(10): 107813, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37810211
13.
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of the Monoclonal Antibody MHAA4549A in Patients With Acute Uncomplicated Influenza A Infection.
Open Forum Infect Dis
; 9(2): ofab630, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35106315
14.
Surfactant protein D is a biomarker of influenza-related pediatric lung injury.
Pediatr Pulmonol
; 57(2): 519-528, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34842360
15.
Genetic deletion of JAM-C reveals a role in myeloid progenitor generation.
Blood
; 113(9): 1919-28, 2009 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19109565
16.
Early Amplified Respiratory Bioactive Lipid Response Is Associated With Worse Outcomes in Pediatric Influenza-Related Respiratory Failure.
Open Forum Infect Dis
; 7(5): ofaa122, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32420403
17.
Pharmacokinetics of the Monoclonal Antibody MHAA4549A Administered in Combination With Oseltamivir in Patients Hospitalized With Severe Influenza A Infection.
J Clin Pharmacol
; 60(11): 1509-1518, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32621543
18.
Correlation of Cytomegalovirus (CMV) Disease Severity and Mortality With CMV Viral Burden in CMV-Seropositive Donor and CMV-Seronegative Solid Organ Transplant Recipients.
Open Forum Infect Dis
; 6(2): ofz003, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30775403
19.
In Vivo Assessment of Antibody-Dependent Enhancement of Influenza B Infection.
Toxicol Sci
; 169(2): 409-421, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30796434
20.
Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE.
Lupus Sci Med
; 2(1): e000080, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25861459