Detalhe da pesquisa
1.
Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2).
Bioorg Med Chem Lett
; 24(2): 515-9, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24374270
2.
Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
Bioorg Med Chem Lett
; 23(2): 569-73, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23232060
3.
Synthesis and structure-activity relationship of 2-arylamino-4-aryl-pyrimidines as potent PAK1 inhibitors.
Bioorg Med Chem Lett
; 23(14): 4072-5, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23756368
4.
Synthesis and Biological Evaluation of Pyrazolo[1,5-a]pyrimidine Compounds as Potent and Selective Pim-1 Inhibitors.
ACS Med Chem Lett
; 6(1): 63-7, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25589932
5.
A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas.
Neoplasia
; 16(5): 403-12, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24953177
6.
Pharmacologic activation of PKM2 slows lung tumor xenograft growth.
Mol Cancer Ther
; 12(8): 1453-60, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23720766
7.
Discovery of Novel Putative Inhibitors of UDP-GlcNAc 2-Epimerase as Potent Antibacterial Agents.
ACS Med Chem Lett
; 4(12): 1142-1147, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24443700
8.
Epigenetic drug discovery: targeting DNA methyltransferases.
J Biomol Screen
; 17(1): 2-17, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21965114