Detalhe da pesquisa
1.
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.
Nature
; 615(7952): 490-498, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890227
2.
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Nature
; 556(7699): 113-117, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590092
3.
The Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2.
J Immunol
; 207(10): 2551-2560, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635586
4.
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Nat Immunol
; 10(6): 579-86, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19412184
5.
Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion.
Proc Natl Acad Sci U S A
; 113(48): E7778-E7787, 2016 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27856732
6.
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1.
Proc Natl Acad Sci U S A
; 112(23): 7231-6, 2015 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25995365
8.
How metabolism generates signals during innate immunity and inflammation.
J Biol Chem
; 288(32): 22893-8, 2013 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23798679
9.
The GOLD domain-containing protein TMED1 is involved in interleukin-33 signaling.
J Biol Chem
; 288(8): 5616-23, 2013 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23319592
10.
Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15.
J Biol Chem
; 288(35): 25066-25075, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873932
11.
Two for the price of one: itaconate and its derivatives as an anti-infective and anti-inflammatory immunometabolite.
Curr Opin Immunol
; 80: 102268, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36446152
12.
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Cell Metab
; 34(3): 487-501.e8, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35235776
13.
Regulators of TLR4 signaling by endotoxins.
Subcell Biochem
; 53: 153-71, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20593266
14.
The Role of HIF in Immunity and Inflammation.
Cell Metab
; 32(4): 524-536, 2020 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853548
15.
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.
Cell Metab
; 32(3): 468-478.e7, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32791101
16.
Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation.
Cell Rep
; 29(1): 151-161.e5, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31577945
17.
The itaconate family of immunomodulators grows.
Nat Metab
; 4(5): 499-500, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35655025
18.
Glutathione and Glutathione Transferase Omega 1 as Key Posttranslational Regulators in Macrophages.
Microbiol Spectr
; 5(1)2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28102119
19.
Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors.
Front Immunol
; 8: 1300, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29081778
20.
The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction.
Mol Immunol
; 41(6-7): 577-82, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15219996