Detalhe da pesquisa
1.
ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia.
Haematologica
; 105(9): 2286-2297, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33054053
2.
A phase I trial to determine safety and pharmacokinetics of ASLAN002, an oral MET superfamily kinase inhibitor, in patients with advanced or metastatic solid cancers.
Invest New Drugs
; 36(5): 886-894, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29766337
3.
Rhinovirus-induced interferon production is not deficient in well controlled asthma.
Thorax
; 69(3): 240-6, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24127021
4.
Rhinovirus 16-induced IFN-α and IFN-ß are deficient in bronchoalveolar lavage cells in asthmatic patients.
J Allergy Clin Immunol
; 129(6): 1506-1514.e6, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22657407
5.
First-in-Human Study With the Inhaled TLR9 Oligonucleotide Agonist AZD1419 Results in Interferon Responses in the Lung, and Is Safe and Well-Tolerated.
Clin Pharmacol Ther
; 104(2): 335-345, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29134633
6.
RON kinase: A target for treatment of cancer-induced bone destruction and osteoporosis.
Sci Transl Med
; 9(374)2017 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28123075
7.
Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists.
ACS Med Chem Lett
; 8(9): 981-986, 2017 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28947948
8.
Rapid simultaneous cloning of drug targets from multiple mammalian species.
Altern Lab Anim
; 34(3): 295-303, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16831061
9.
The development and characterization of an in vitro model of psoriasis.
J Invest Dermatol
; 123(5): 892-901, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15482477
10.
TLR3, TLR4 and TLRs7-9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma.
PLoS One
; 8(6): e65921, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23824215
11.
CpG-containing immunostimulatory DNA sequences elicit TNF-alpha-dependent toxicity in rodents but not in humans.
J Clin Invest
; 119(9): 2564-76, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19726873