Detalhe da pesquisa
1.
WRN helicase and mismatch repair complexes independently and synergistically disrupt cruciform DNA structures.
EMBO J
; 42(3): e111998, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36541070
2.
Neuronal enhancers are hotspots for DNA single-strand break repair.
Nature
; 593(7859): 440-444, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33767446
3.
Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
Nature
; 586(7828): 292-298, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32999459
4.
A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1.
Genes Dev
; 31(4): 353-369, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28279982
5.
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
Nucleic Acids Res
; 50(3): 1484-1500, 2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35037045
6.
A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family.
Nucleic Acids Res
; 49(16): 9294-9309, 2021 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387694
7.
Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition.
Nucleic Acids Res
; 49(16): 9310-9326, 2021 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387696
8.
Genetic and functional insights into CDA-I prevalence and pathogenesis.
J Med Genet
; 58(3): 185-195, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32518175
9.
RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.
EMBO J
; 36(14): 2047-2060, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607004
10.
Microhomologies are prevalent at Cas9-induced larger deletions.
Nucleic Acids Res
; 47(14): 7402-7417, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127293
11.
The Chemical Biology of Human Metallo-ß-Lactamase Fold Proteins.
Trends Biochem Sci
; 41(4): 338-355, 2016 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26805042
12.
A hydroxamic-acid-containing nucleoside inhibits DNA repair nuclease SNM1A.
Org Biomol Chem
; 17(35): 8094-8105, 2019 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31380542
13.
Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair.
Genes Dev
; 25(17): 1859-70, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21896658
14.
XPF-ERCC1: Linchpin of DNA crosslink repair.
PLoS Genet
; 16(4): e1008616, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32271747
15.
The structures of the SNM1A and SNM1B/Apollo nuclease domains reveal a potential basis for their distinct DNA processing activities.
Nucleic Acids Res
; 43(22): 11047-60, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26582912
16.
CSB interacts with SNM1A and promotes DNA interstrand crosslink processing.
Nucleic Acids Res
; 43(1): 247-58, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505141
17.
Structural Basis of Metallo-ß-Lactamase Inhibition by Captopril Stereoisomers.
Antimicrob Agents Chemother
; 60(1): 142-50, 2016 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26482303
18.
Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.
PLoS Genet
; 8(8): e1002884, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22912599
19.
XPF protein levels determine sensitivity of malignant melanoma cells to oxaliplatin chemotherapy: suitability as a biomarker for patient selection.
Int J Cancer
; 134(6): 1495-503, 2014 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23982883
20.
Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases.
J Biol Chem
; 287(31): 26254-67, 2012 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22692201