Detalhe da pesquisa
1.
A neurodevelopmental disorder associated with a loss-of-function missense mutation in RAB35.
J Biol Chem
; 300(4): 107124, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38432637
2.
Heed a decade of calls for antibody validation.
Nature
; 620(7974): 492, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37582877
3.
The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics.
J Biol Chem
; 298(9): 102320, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35933016
4.
SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis.
J Biol Chem
; 296: 100306, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33476648
5.
A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy.
J Biol Chem
; 293(12): 4566-4574, 2018 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29352104
6.
Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J Biol Chem
; 293(33): 12832-12842, 2018 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945973
7.
Epileptic Encephalopathy Caused by Mutations in the Guanine Nucleotide Exchange Factor DENND5A.
Am J Hum Genet
; 99(6): 1359-1367, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27866705
8.
Intersectin-s interaction with DENND2B facilitates recycling of epidermal growth factor receptor.
EMBO Rep
; 18(12): 2119-2130, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29030480
9.
Regulation of DENND3, the exchange factor for the small GTPase Rab12 through an intramolecular interaction.
J Biol Chem
; 292(17): 7274-7282, 2017 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28249939
10.
Correction: The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics.
J Biol Chem
; 298(12): 102718, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36446242
11.
The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes.
Mol Cell
; 37(3): 370-82, 2010 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20159556
12.
Regulation of Cancer Cell Behavior by the Small GTPase Rab13.
J Biol Chem
; 291(19): 9929-37, 2016 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27044746
13.
Rab13 Traffics on Vesicles Independent of Prenylation.
J Biol Chem
; 291(20): 10726-35, 2016 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26969162
14.
Sacs knockout mice present pathophysiological defects underlying autosomal recessive spastic ataxia of Charlevoix-Saguenay.
Hum Mol Genet
; 24(3): 727-39, 2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25260547
15.
The juxtamembrane region of synaptotagmin 1 interacts with dynamin 1 and regulates vesicle fission during compensatory endocytosis in endocrine cells.
J Cell Sci
; 128(12): 2229-35, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25964652
16.
Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy.
EMBO Rep
; 16(6): 709-18, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25925668
17.
LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation.
EMBO Rep
; 16(1): 79-86, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25427558
18.
SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination.
Mol Cell
; 36(6): 1034-47, 2009 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20064468
19.
Endocytic membrane trafficking and neurodegenerative disease.
Cell Mol Life Sci
; 73(8): 1529-45, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26721251
20.
Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors.
J Biol Chem
; 290(29): 17999-18008, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26055712