Detalhe da pesquisa
1.
EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation.
PLoS Biol
; 21(3): e3002034, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36888606
2.
Signals from the lysosome: a control centre for cellular clearance and energy metabolism.
Nat Rev Mol Cell Biol
; 14(5): 283-96, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23609508
3.
Brain Disorders Due to Lysosomal Dysfunction.
Annu Rev Neurosci
; 39: 277-95, 2016 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27090953
4.
Investigation on lysosomal accumulation by a quantitative analysis of 2D phase-maps in digital holography microscopy.
Cytometry A
; 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38420869
5.
Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I.
Int J Mol Sci
; 23(3)2022 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35162981
6.
FGF signalling regulates bone growth through autophagy.
Nature
; 528(7581): 272-5, 2015 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26595272
7.
Fingolimod phosphate inhibits astrocyte inflammatory activity in mucolipidosis IV.
Hum Mol Genet
; 27(15): 2725-2738, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29771310
8.
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.
PLoS Genet
; 13(1): e1006552, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28056084
9.
gene2drug: a computational tool for pathway-based rational drug repositioning.
Bioinformatics
; 34(9): 1498-1505, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29236977
10.
Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells.
Kidney Int
; 89(4): 862-73, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26994576
11.
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
EMBO J
; 31(5): 1095-108, 2012 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343943
12.
A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data.
BMC Bioinformatics
; 16: 279, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26334955
13.
The phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activation.
J Biol Chem
; 289(24): 17054-69, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24770416
14.
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies.
Cell Death Differ
; 31(2): 217-238, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38238520
15.
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function.
Sci Adv
; 9(1): eade1694, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36608116
16.
The Regulation of MiTF/TFE Transcription Factors Across Model Organisms: from Brain Physiology to Implication for Neurodegeneration.
Mol Neurobiol
; 59(8): 5000-5023, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665902
17.
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis.
Nat Commun
; 13(1): 536, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35087090
18.
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease.
EMBO Mol Med
; 14(9): e15377, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35929194
19.
Lysosomal calcium and autophagy.
Int Rev Cell Mol Biol
; 362: 141-170, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34253294
20.
The rapidly evolving view of lysosomal storage diseases.
EMBO Mol Med
; 13(2): e12836, 2021 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33459519