Pesquisa | BVS IEC

1.

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters.

Ventura, Andrea; Young, Amanda G; Winslow, Monte M; Lintault, Laura; Meissner, Alex; Erkeland, Stefan J; Newman, Jamie; Bronson, Roderick T; Crowley, Denise; Stone, James R; Jaenisch, Rudolf; Sharp, Phillip A; Jacks, Tyler.

Cell ; 132(5): 875-86, 2008 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-18329372

2.

Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission.

Nehme, Ralda; Zuccaro, Emanuela; Ghosh, Sulagna Dia; Li, Chenchen; Sherwood, John L; Pietilainen, Olli; Barrett, Lindy E; Limone, Francesco; Worringer, Kathleen A; Kommineni, Sravya; Zang, Ying; Cacchiarelli, Davide; Meissner, Alex; Adolfsson, Rolf; Haggarty, Stephen; Madison, Jon; Muller, Matthias; Arlotta, Paola; Fu, Zhanyan; Feng, Guoping; Eggan, Kevin.

Cell Rep ; 23(8): 2509-2523, 2018 05 22.

Artigo em Inglês | MEDLINE | ID: mdl-29791859

3.

Politically correct human embryonic stem cells?

Jaenisch, Rudolf; Meissner, Alex.

N Engl J Med ; 354(11): 1208-9; author reply 1208-9, 2006 Mar 16.

Artigo em Inglês | MEDLINE | ID: mdl-16540629

4.

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.

De Jager, Philip L; Srivastava, Gyan; Lunnon, Katie; Burgess, Jeremy; Schalkwyk, Leonard C; Yu, Lei; Eaton, Matthew L; Keenan, Brendan T; Ernst, Jason; McCabe, Cristin; Tang, Anna; Raj, Towfique; Replogle, Joseph; Brodeur, Wendy; Gabriel, Stacey; Chai, High S; Younkin, Curtis; Younkin, Steven G; Zou, Fanggeng; Szyf, Moshe; Epstein, Charles B; Schneider, Julie A; Bernstein, Bradley E; Meissner, Alex; Ertekin-Taner, Nilufer; Chibnik, Lori B; Kellis, Manolis; Mill, Jonathan; Bennett, David A.

Nat Neurosci ; 17(9): 1156-63, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25129075

5.

Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci.

Zacharek, Sima J; Fillmore, Christine M; Lau, Allison N; Gludish, David W; Chou, Alan; Ho, Joshua W K; Zamponi, Raffaella; Gazit, Roi; Bock, Christoph; Jäger, Natalie; Smith, Zachary D; Kim, Tae-min; Saunders, Arven H; Wong, Janice; Lee, Joo-Hyeon; Roach, Rebecca R; Rossi, Derrick J; Meissner, Alex; Gimelbrant, Alexander A; Park, Peter J; Kim, Carla F.

Cell Stem Cell ; 9(3): 272-81, 2011 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-21885022

6.

G1 arrest and differentiation can occur independently of Rb family function.

Wirt, Stacey E; Adler, Adam S; Gebala, Véronique; Weimann, James M; Schaffer, Bethany E; Saddic, Louis A; Viatour, Patrick; Vogel, Hannes; Chang, Howard Y; Meissner, Alex; Sage, Julien.

J Cell Biol ; 191(4): 809-25, 2010 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-21059851

7.

Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses.

Amit, Ido; Garber, Manuel; Chevrier, Nicolas; Leite, Ana Paula; Donner, Yoni; Eisenhaure, Thomas; Guttman, Mitchell; Grenier, Jennifer K; Li, Weibo; Zuk, Or; Schubert, Lisa A; Birditt, Brian; Shay, Tal; Goren, Alon; Zhang, Xiaolan; Smith, Zachary; Deering, Raquel; McDonald, Rebecca C; Cabili, Moran; Bernstein, Bradley E; Rinn, John L; Meissner, Alex; Root, David E; Hacohen, Nir; Regev, Aviv.

Science ; 326(5950): 257-63, 2009 Oct 09.

Artigo em Inglês | MEDLINE | ID: mdl-19729616

8.

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing.

Linhart, Heinz G; Lin, Haijiang; Yamada, Yasuhiro; Moran, Eva; Steine, Eveline J; Gokhale, Sumita; Lo, Grace; Cantu, Erika; Ehrich, Mathias; He, Timothy; Meissner, Alex; Jaenisch, Rudolf.

Genes Dev ; 21(23): 3110-22, 2007 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-18056424

9.

Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus.

Blelloch, Robert; Wang, Zhongde; Meissner, Alex; Pollard, Steven; Smith, Austin; Jaenisch, Rudolf.

Stem Cells ; 24(9): 2007-13, 2006 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-16709876

10.

A bivalent chromatin structure marks key developmental genes in embryonic stem cells.

Bernstein, Bradley E; Mikkelsen, Tarjei S; Xie, Xiaohui; Kamal, Michael; Huebert, Dana J; Cuff, James; Fry, Ben; Meissner, Alex; Wernig, Marius; Plath, Kathrin; Jaenisch, Rudolf; Wagschal, Alexandre; Feil, Robert; Schreiber, Stuart L; Lander, Eric S.

Cell ; 125(2): 315-26, 2006 Apr 21.

Artigo em Inglês | MEDLINE | ID: mdl-16630819

11.

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.

Yamada, Yasuhiro; Jackson-Grusby, Laurie; Linhart, Heinz; Meissner, Alex; Eden, Amir; Lin, Haijiang; Jaenisch, Rudolf.

Proc Natl Acad Sci U S A ; 102(38): 13580-5, 2005 Sep 20.

Artigo em Inglês | MEDLINE | ID: mdl-16174748

12.

Broader implications of defining standards for the pluripotency of iPSCs.

Daley, George Q; Lensch, M William; Jaenisch, Rudolf; Meissner, Alex; Plath, Kathrin; Yamanaka, Shinya.

Cell Stem Cell ; 4(3): 200-1; author reply 202, 2009 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-19265657

BVS IEC

Instituto Evandro Chagas

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