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1.
J Med Syst ; 45(7): 75, 2021 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-34101042

RESUMO

Coronavirus disease 2019 (COVID-19) is an infectious disease with first symptoms similar to the flu. COVID-19 appeared first in China and very quickly spreads to the rest of the world, causing then the 2019-20 coronavirus pandemic. In many cases, this disease causes pneumonia. Since pulmonary infections can be observed through radiography images, this paper investigates deep learning methods for automatically analyzing query chest X-ray images with the hope to bring precision tools to health professionals towards screening the COVID-19 and diagnosing confirmed patients. In this context, training datasets, deep learning architectures and analysis strategies have been experimented from publicly open sets of chest X-ray images. Tailored deep learning models are proposed to detect pneumonia infection cases, notably viral cases. It is assumed that viral pneumonia cases detected during an epidemic COVID-19 context have a high probability to presume COVID-19 infections. Moreover, easy-to-apply health indicators are proposed for estimating infection status and predicting patient status from the detected pneumonia cases. Experimental results show possibilities of training deep learning models over publicly open sets of chest X-ray images towards screening viral pneumonia. Chest X-ray test images of COVID-19 infected patients are successfully diagnosed through detection models retained for their performances. The efficiency of proposed health indicators is highlighted through simulated scenarios of patients presenting infections and health problems by combining real and synthetic health data.


Assuntos
COVID-19/diagnóstico por imagem , Aprendizado Profundo , Pneumonia Viral/diagnóstico por imagem , Radiografia Torácica , Algoritmos , Humanos , Redes Neurais de Computação , Raios X
2.
J Healthc Inform Res ; 6(4): 442-460, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36688121

RESUMO

A novel approach of data augmentation based on irregular superpixel decomposition is proposed. This approach called SuperpixelGridMasks permits to extend original image datasets that are required by training stages of machine learning-related analysis architectures towards increasing their performances. Three variants named SuperpixelGridCut, SuperpixelGridMean, and SuperpixelGridMix are presented. These grid-based methods produce a new style of image transformations using the dropping and fusing of information. Extensive experiments using various image classification models as well as precision health and surrounding real-world datasets show that baseline performances can be significantly outperformed using our methods. The comparative study also shows that our methods can overpass the performances of other data augmentations. SuperpixelGridCut, SuperpixelGridMean, and SuperpixelGridMix codes are publicly available at https://github.com/hammoudiproject/SuperpixelGridMasks.

3.
J Mol Graph Model ; 111: 108103, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-34959149

RESUMO

Proteins are essential to nearly all cellular mechanism and the effectors of the cells activities. As such, they often interact through their surface with other proteins or other cellular ligands such as ions or organic molecules. The evolution generates plenty of different proteins, with unique abilities, but also proteins with related functions hence similar 3D surface properties (shape, physico-chemical properties, …). The protein surfaces are therefore of primary importance for their activity. In the present work, we assess the ability of different methods to detect such similarities based on the geometry of the protein surfaces (described as 3D meshes), using either their shape only, or their shape and the electrostatic potential (a biologically relevant property of proteins surface). Five different groups participated in this contest using the shape-only dataset, and one group extended its pre-existing method to handle the electrostatic potential. Our comparative study reveals both the ability of the methods to detect related proteins and their difficulties to distinguish between highly related proteins. Our study allows also to analyze the putative influence of electrostatic information in addition to the one of protein shapes alone. Finally, the discussion permits to expose the results with respect to ones obtained in the previous contests for the extended method. The source codes of each presented method have been made available online.


Assuntos
Proteínas , Ligantes , Modelos Moleculares , Domínios Proteicos , Eletricidade Estática
4.
Smart Health (Amst) ; 19: 100144, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33521223

RESUMO

Wearing face masks appears as a solution for limiting the spread of COVID-19. In this context, efficient recognition systems are expected for checking that people faces are masked in regulated areas. Hence, a large dataset of masked faces is necessary for training deep learning models towards detecting people wearing masks and those not wearing masks. Currently, there are no available large dataset of masked face images that permits to check if faces are correctly masked or not. Indeed, many people are not correctly wearing their masks due to bad practices, bad behaviors or vulnerability of individuals (e.g., children, old people). For these reasons, several mask wearing campaigns intend to sensitize people about this problem and good practices. In this sense, this work proposes an image editing approach and three types of masked face detection dataset; namely, the Correctly Masked Face Dataset (CMFD), the Incorrectly Masked Face Dataset (IMFD) and their combination for the global masked face detection (MaskedFace-Net). Realistic masked face datasets are proposed with a twofold objective: i) detecting people having their faces masked or not masked, ii) detecting faces having their masks correctly worn or incorrectly worn (e.g.; at airport portals or in crowds). To the best of our knowledge, no large dataset of masked faces provides such a granularity of classification towards mask wearing analysis. Moreover, this work globally presents the applied mask-to-face deformable model for permitting the generation of other masked face images, notably with specific masks. Our datasets of masked faces (137,016 images) are available at https://github.com/cabani/MaskedFace-Net. The dataset of face images Flickr-Faces-HQ3 (FFHQ), publicly made available online by NVIDIA Corporation, has been used for generating MaskedFace-Net.

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