Detalhe da pesquisa
1.
Cytotoxic Activity, Topoisomerase I Inhibition and In Silico Studies of New Sesquiterpene-aryl Ester Derivatives of (-) Drimenol.
Molecules
; 28(9)2023 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175368
2.
QSAR-driven synthesis of antiproliferative chalcones against SH-SY5Y cancer cells: Design, biological evaluation, and redesign.
Arch Pharm (Weinheim)
; 355(7): e2200042, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35435270
3.
Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin.
Molecules
; 27(3)2022 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164192
4.
Combined 3D-QSAR and docking analysis for the design and synthesis of chalcones as potent and selective monoamine oxidase B inhibitors.
Bioorg Chem
; 108: 104689, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571810
5.
3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
Bioorg Chem
; 101: 103964, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32474182
6.
New 2,6,9-trisubstituted purine derivatives as Bcr-Abl and Btk inhibitors and as promising agents against leukemia.
Bioorg Chem
; 94: 103361, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699386
7.
Design, synthesis, antifungal activity, and structure-activity relationship studies of chalcones and hybrid dihydrochromane-chalcones.
Mol Divers
; 24(3): 603-615, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31161394
8.
Three-Dimensional Quantitative Structure-Activity Relationships (3D-QSAR) on a Series of Piperazine-Carboxamides Fatty Acid Amide Hydrolase (FAAH) Inhibitors as a Useful Tool for the Design of New Cannabinoid Ligands.
Int J Mol Sci
; 20(10)2019 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31117309
9.
Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays.
Int J Mol Sci
; 21(1)2019 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31881717
10.
Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human ß3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles.
Molecules
; 23(5)2018 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29772697
11.
A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections.
Molecules
; 23(7)2018 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30029513
12.
Insights into the Structural Requirements of Potent Brassinosteroids as Vegetable Growth Promoters Using Second-Internode Elongation as Biological Activity: CoMFA and CoMSIA Studies.
Int J Mol Sci
; 18(12)2017 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29258205
13.
2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human ß3-Adrenergic Activity.
Molecules
; 22(3)2017 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28273884
14.
Arylamines QSAR-Based Design and Molecular Dynamics of New Phenylthiophene and Benzimidazole Derivatives with Affinity for the C111, Y268, and H73 Sites of SARS-CoV-2 PLpro Enzyme.
Pharmaceuticals (Basel)
; 17(5)2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38794177
15.
Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives.
Steroids
; 190: 109153, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36481216
16.
QSAR Studies, Synthesis, and Biological Evaluation of New Pyrimido-Isoquinolin-Quinone Derivatives against Methicillin-Resistant Staphylococcus aureus.
Pharmaceuticals (Basel)
; 16(11)2023 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38004487
17.
In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular docking and molecular dynamics studies.
J Biomol Struct Dyn
; 41(22): 13250-13259, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36718094
18.
Design, Synthesis, and Structure-Activity Relationship Studies of New Quinone Derivatives as Antibacterial Agents.
Antibiotics (Basel)
; 12(6)2023 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37370384
19.
Design, Synthesis, and Molecular Modeling Studies of a Novel Benzimidazole as an Aromatase Inhibitor.
ACS Omega
; 7(18): 16152-16163, 2022 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35571854
20.
Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia.
Pharmaceutics
; 14(6)2022 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35745866