Detalhe da pesquisa
1.
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Cell
; 153(3): 707-20, 2013 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23622250
2.
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases.
Mol Syst Biol
; 10: 743, 2014 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25080494
3.
RNA interference targeting ANGPTL3 for triglyceride and cholesterol lowering: phase 1 basket trial cohorts.
Nat Med
; 29(9): 2216-2223, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37626170
4.
RNA Interference Therapy Targeting Apolipoprotein C-III in Hypertriglyceridemia.
NEJM Evid
; 2(12): EVIDoa2200325, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38320498
5.
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17.
Nature
; 442(7105): 916-9, 2006 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-16862116
6.
Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a).
Nat Med
; 28(1): 96-103, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027752
7.
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Neuron
; 54(5): 713-20, 2007 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-17553421
8.
Analysis of UBQLN1 variants in a Polish Alzheimer's disease patient: control series.
Dement Geriatr Cogn Disord
; 25(4): 366-71, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18340109
9.
APOE epsilon 4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway.
BMC Neurol
; 8: 9, 2008 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18416843
10.
Risk-reducing effect of education in Alzheimer's disease.
Int J Geriatr Psychiatry
; 23(11): 1156-62, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18484674
11.
A family with tau-negative frontotemporal dementia and neuronal intranuclear inclusions linked to chromosome 17.
Brain
; 129(Pt 4): 853-67, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16401619
12.
Discovery of 6-(Fluoro-(18)F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs).
J Med Chem
; 59(10): 4778-89, 2016 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27088900
13.
LRRK2 mutations are not common in Alzheimer's disease.
Mech Ageing Dev
; 126(11): 1201-5, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16087219
14.
An internal rearrangement in an Arabidopsis inverted repeat locus impairs DNA methylation triggered by the locus.
Genetics
; 166(1): 437-48, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15020434
15.
Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis.
Int J Mol Epidemiol Genet
; 1(1): 19-30, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-21537449
16.
Evidence for an association between KIBRA and late-onset Alzheimer's disease.
Neurobiol Aging
; 31(6): 901-9, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18789830
17.
Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies.
Am J Hum Genet
; 80(1): 126-39, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17160900
18.
Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms.
Am J Hum Genet
; 80(4): 769-78, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17357082
19.
Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration.
Hum Mol Genet
; 15(20): 2988-3001, 2006 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16950801
20.
High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy.
Hum Mol Genet
; 14(21): 3281-92, 2005 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16195395