Detalhe da pesquisa
1.
Novel pyrrolidine heterocycles as CCR1 antagonists.
Bioorg Med Chem Lett
; 20(18): 5477-9, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20708929
2.
Synthesis and structure-activity relationships of new disubstituted phenyl-containing 3,4-diamino-3-cyclobutene-1,2-diones as CXCR2 receptor antagonists.
Bioorg Med Chem Lett
; 18(6): 1864-8, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18304809
3.
3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists.
Bioorg Med Chem Lett
; 18(1): 228-31, 2008 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18006311
4.
Synthesis and structure-activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists.
Bioorg Med Chem Lett
; 18(4): 1318-22, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18242983
5.
Discovery of 2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): a potent, orally bioavailable CXCR2/CXCR1 receptor antagonist.
J Med Chem
; 49(26): 7603-6, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17181143
6.
Small molecule chemokine mimetics suggest a molecular basis for the observation that CXCL10 and CXCL11 are allosteric ligands of CXCR3.
Br J Pharmacol
; 166(3): 912-23, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21895630
7.
CC chemokine receptor small molecule antagonists in the treatment of rheumatoid arthritis and other diseases: a current view.
Curr Top Med Chem
; 10(13): 1250-67, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20536422
8.
Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.
J Med Chem
; 52(5): 1295-301, 2009 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19183043
9.
C(4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists.
Bioorg Med Chem Lett
; 17(13): 3778-83, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17459706
10.
Identification of CXCR3 receptor agonists in combinatorial small-molecule libraries.
Biochem Biophys Res Commun
; 349(1): 221-8, 2006 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-16930533
11.
Synthesis and structure-activity relationships of 3,4-diaminocyclobut-3-ene-1,2-dione CXCR2 antagonists.
Bioorg Med Chem Lett
; 16(15): 4107-10, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16697193
12.
Chemokine receptors as targets in medicinal chemistry and drug discovery.
Curr Top Med Chem
; 10(13): 1249, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20681947