Detalhe da pesquisa
1.
How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell.
PLoS Pathog
; 19(7): e1011522, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37498954
2.
First comprehensive untargeted metabolomics study of suramin-treated Trypanosoma brucei: an integrated data analysis workflow from multifactor data modelling to functional analysis.
Metabolomics
; 20(2): 25, 2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38393408
3.
A Trypanosoma cruzi phosphoglycerate kinase isoform with a Per-Arnt-Sim domain acts as a possible sensor for intracellular conditions.
Exp Parasitol
; 251: 108574, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37353138
4.
Biogenesis and metabolic homeostasis of trypanosomatid glycosomes: New insights and new questions.
J Eukaryot Microbiol
; 69(6): e12897, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35175680
5.
Anonaine from Annona crassiflora inhibits glutathione S-transferase and improves cypermethrin activity on Rhipicephalus (Boophilus) microplus (Canestrini, 1887).
Exp Parasitol
; 243: 108398, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36228702
6.
Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.
Biochem J
; 477(22): 4425-4441, 2020 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33141153
7.
Carbohydrate metabolism in trypanosomatids: New insights revealing novel complexity, diversity and species-unique features.
Exp Parasitol
; 224: 108102, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33775649
8.
Pyruvate kinase from Plasmodium falciparum: Structural and kinetic insights into the allosteric mechanism.
Biochem Biophys Res Commun
; 532(3): 370-376, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32878705
9.
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.
FASEB J
; 33(11): 13002-13013, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31525300
10.
The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction.
Biochem J
; 476(2): 179-191, 2019 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30404924
11.
An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor.
Biochem J
; 475(10): 1821-1837, 2018 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29748232
12.
Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites.
Biochim Biophys Acta
; 1863(5): 1038-48, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26384872
13.
Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.
Biochim Biophys Acta Gen Subj
; 1861(11 Pt A): 2830-2842, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28778484
14.
TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.
Nucleic Acids Res
; 43(Database issue): D637-44, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25300491
15.
The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism.
Proteins
; 84(8): 1075-96, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27093562
16.
Trypanosoma evansi contains two auxiliary enzymes of glycolytic metabolism: Phosphoenolpyruvate carboxykinase and pyruvate phosphate dikinase.
Exp Parasitol
; 165: 7-15, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26968775
17.
Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Mol Microbiol
; 94(6): 1315-29, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25315291
18.
Synthesis and evaluation of novel prenylated chalcone derivatives as anti-leishmanial and anti-trypanosomal compounds.
Bioorg Med Chem Lett
; 25(16): 3342-5, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26055530
19.
Pyruvate kinases have an intrinsic and conserved decarboxylase activity.
Biochem J
; 458(2): 301-11, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24328825
20.
Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.
J Biol Chem
; 288(25): 18494-505, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23665470