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19.
Eksp Med Morfol ; 15(1): 8-14, 1976.
Artigo em Búlgaro | MEDLINE | ID: mdl-131683

RESUMO

The author examined the action of leucemic sera (first attack, repapse and remission) on the reactivity of lymphocytes, obtained from patients with acute myeloblastic (AML) in mixed cultures of lymphocytes, which was compared with the reactivity in the medium of fetal calf serum and pool of normal human serum. Twelve out of 21 Leucemic sera, obtained from patients with AML during their first attack or relapse inhibited completely the mixed lympholytec cultures under autologic conditions. Eight leucemic sera with established inhibiting action under autologic conditions preserved it under allogenic conditions as well. Sera of patients with acute myeloblastic leucosis during remission did not have inhibiting action on mixed lymphocytic cultures. These results suggested the presence of factor(s) in the sera of patients with acute myeloblastic leucosis during the first attack or relapse, which inhibited mixed lymphocytic cultures.


Assuntos
Soros Imunes/farmacologia , Leucemia Mieloide Aguda/imunologia , Leucócitos/efeitos dos fármacos , Linfócitos/efeitos dos fármacos , Animais , Bovinos , Humanos , Leucócitos/imunologia , Teste de Cultura Mista de Linfócitos , Linfócitos/imunologia , Recidiva , Remissão Espontânea
20.
Vutr Boles ; 23(2): 92-7, 1984.
Artigo em Búlgaro | MEDLINE | ID: mdl-6741116

RESUMO

The basal blood level of the thyrotropic hormone (TTH) was radioimmunologically determined in 160 patients with diabetes mellitus. A significant increase of its average level was established versus that in the control group of healthy subjects. The changes found showed no dependence on sex, age, duration and type of disease, light deviations from the standard body weight and the differences in drug treatment. A light correlation was established between the thyrotropinemia and glycemia as well as an insignificant dynamics of the hormonal blood level after the compensation of the diabetes. The higher TTH level established in the patients without retinopathy requires further studies on the significance of that fact.


Assuntos
Diabetes Mellitus/sangue , Tireotropina/sangue , Adulto , Idoso , Glicemia/análise , Diabetes Mellitus Tipo 1/sangue , Diabetes Mellitus Tipo 2/sangue , Nefropatias Diabéticas/sangue , Retinopatia Diabética/sangue , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
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