Detalhe da pesquisa
1.
Proteostasis of Islet Amyloid Polypeptide: A Molecular Perspective of Risk Factors and Protective Strategies for Type II Diabetes.
Chem Rev
; 121(3): 1845-1893, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33427465
2.
Dipyridamole for tracking amyloidogenic proteins aggregation and enhancing polyubiquitination.
Arch Biochem Biophys
; 728: 109354, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35863477
3.
Silybins are stereospecific regulators of the 20S proteasome.
Bioorg Med Chem
; 66: 116813, 2022 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35576657
4.
Aß and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease?
Molecules
; 27(16)2022 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36014310
5.
Investigation on the solid-phase synthesis of silybin prodrugs and their timed-release.
Bioorg Med Chem
; 50: 116478, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34695708
6.
Probing the helical stability in a VEGF-mimetic peptide.
Bioorg Chem
; 116: 105379, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34563997
7.
Symmetry-breaking transitions in the early steps of protein self-assembly.
Eur Biophys J
; 49(2): 175-191, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32123956
8.
Substitution of the Native Zn(II) with Cd(II), Co(II) and Ni(II) Changes the Downhill Unfolding Mechanism of Ros87 to a Completely Different Scenario.
Int J Mol Sci
; 21(21)2020 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33167398
9.
The Ionophoric Activity of a Pro-Apoptotic VEGF165 Fragment on HUVEC Cells.
Int J Mol Sci
; 21(8)2020 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32325956
10.
Cooperative Binding of the Cationic Porphyrin Tris-T4 Enhances Catalytic Activity of 20S Proteasome Unveiling a Complex Distribution of Functional States.
Int J Mol Sci
; 21(19)2020 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33003385
11.
Multiple functions of insulin-degrading enzyme: a metabolic crosslight?
Crit Rev Biochem Mol Biol
; 52(5): 554-582, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28635330
12.
The insulin-degrading enzyme is an allosteric modulator of the 20S proteasome and a potential competitor of the 19S.
Cell Mol Life Sci
; 75(18): 3441-3456, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-29594388
13.
Corrigendum to "Silybins are stereospecific regulators of the 20S proteasome" [Bioorgan. Med. Chem. 66 (2022) 116813].
Bioorg Med Chem
; 69: 116895, 2022 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35760736
14.
The Role of Cholesterol in Driving IAPP-Membrane Interactions.
Biophys J
; 111(1): 140-51, 2016 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27410742
15.
Ubiquitin Associates with the N-Terminal Domain of Nerve Growth Factor: The Role of Copper(II) Ions.
Chemistry
; 22(49): 17767-17775, 2016 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27759905
16.
Computational comparison of imidazoline association with the I2 binding site in human monoamine oxidases.
J Chem Inf Model
; 54(4): 1200-7, 2014 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24601544
17.
Synthesis, biophysical characterization and anti-HIV activity of d(TG3AG) Quadruplexes bearing hydrophobic tails at the 5'-end.
Bioorg Med Chem
; 22(3): 960-6, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24433967
18.
Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP.
Biophys J
; 104(1): 173-84, 2013 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23332070
19.
Structural Zn(II) implies a switch from fully cooperative to partly downhill folding in highly homologous proteins.
J Am Chem Soc
; 135(13): 5220-8, 2013 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23484956
20.
Carnosine inhibits Aß(42) aggregation by perturbing the H-bond network in and around the central hydrophobic cluster.
Chembiochem
; 14(5): 583-92, 2013 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23440928