RESUMO
SIGNIFICANCE: Results of this study provide preliminary data on parent strategies for improving compliance with eyeglass treatment in young children, an age group for which previous data are limited. Parent responses provide important insights to support parents of young children who wear eyeglasses and provide preliminary data to guide additional research. PURPOSE: The goal of this exploratory study was to learn more about parents' strategies to improve compliance with eyeglass treatment of young children. METHODS: An online survey of parents of 1-year-old to less than 5-year-old children who wear eyeglasses was conducted. Parents indicated whether they used various strategies to encourage wear and were asked to provide advice for parents of young children recently prescribed eyeglasses. Use of various strategies by age was determined. Open-ended responses regarding advice for other parents were analyzed using qualitative content analysis. RESULTS: The final sample included 104 parents who were predominantly White (81%), non-Hispanic (76%), and college graduates (68%). During the 2 weeks prior to survey completion, 74% of parents reported their child wore their eyeglasses ≥8 hours/day. Use of strategies for improving eyeglass wear varied by child age. The most frequent recommendations that parents provided for other parents were to be consistent in encouraging wear, use social modeling, provide positive reinforcement when the eyeglasses are worn, and ensure that the eyeglasses fit well and were comfortable. CONCLUSIONS: Parents provided many useful insights into their experiences. However, results may not be broadly generalizable, because of the limited diversity and high rate of compliance in the study sample. Further research with more diverse populations and research on effectiveness of various strategies to increase compliance in this age group are recommended to support eyeglass treatment compliance in young children.
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Óculos , Pais , Cooperação do Paciente , Humanos , Pré-Escolar , Feminino , Masculino , Lactente , Inquéritos e Questionários , Ambliopia/terapia , Ambliopia/fisiopatologia , AdultoRESUMO
Infantile hemangioma is the most common soft tissue tumor of infancy. Extensive organ involvement is rare. This report describes an infant with biopsy confirmed infantile hemangioma with diffuse organ involvement causing anemia and failure to thrive. Treatment was initiated with propranolol and led to initial improvement; however, course was complicated by several episodes of respiratory failure secondary to pulmonary edema. Propranolol therapy was interrupted for several months while patient was maintained on a diuretic regimen and treated with vincristine and high-dose corticosteroids. Patient was transitioned back to propranolol and is clinically thriving with objective improvement on radiographic imaging.
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Hemangioma Capilar , Hemangioma , Insuficiência Respiratória , Corticosteroides/uso terapêutico , Antagonistas Adrenérgicos beta , Diuréticos/uso terapêutico , Hemangioma/complicações , Hemangioma/tratamento farmacológico , Hemangioma Capilar/complicações , Hemangioma Capilar/tratamento farmacológico , Humanos , Lactente , Propranolol/uso terapêutico , Insuficiência Respiratória/etiologia , Canal Medular , Resultado do Tratamento , Vincristina/uso terapêuticoRESUMO
Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular tumor that mainly occurs during infancy or early childhood. Approximately 70% of cases are complicated by Kasabach-Merritt phenomenon. Although osseous extension of the primary lesion is relatively common, primary bone involvement by KHE is rare. Given the paucity of literature on primary KHE of the bone, we report a case series of primary KHE of the bone treated at our institution and describe the clinical presentation, radiologic and pathologic findings, management and outcomes.
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Hemangioendotelioma , Síndrome de Kasabach-Merritt , Sarcoma de Kaposi , Neoplasias Vasculares , Adolescente , Criança , Pré-Escolar , Hemangioendotelioma/diagnóstico por imagem , Humanos , Sarcoma de Kaposi/diagnósticoRESUMO
We present a complex case of a neonate, delivered urgently for hydrops fetalis, with a large vascular mass of the extremity, diagnosed postnatally as a congenital hemangioma. The patient suffered immediate cardiac compromise and severe coagulopathy atypical for the diagnosis and subsequently died from these complications. Treatment was imperative but challenging due to a lack of a standardized treatment approach and few historical reports of equally critically ill patients. In this report, we review potential medical and surgical interventions and discuss treatment considerations in similar, life-threatening cases of congenital hemangiomas.
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Insuficiência Cardíaca , Hemangioma , Insuficiência Cardíaca/etiologia , Hemangioma/complicações , Hemangioma/diagnóstico , Humanos , Hidropisia Fetal , Recém-NascidoRESUMO
PURPOSE: To assess interrater and test-retest reliability of the 6th Edition Beery-Buktenica Developmental Test of Visual-Motor Integration (VMI) and test-retest reliability of the VMI Visual Perception Supplemental Test (VMIp) in school-age children. METHODS: Subjects were 163 Native American third- to eighth-grade students with no significant refractive error (astigmatism <1.00 D, myopia <0.75 D, hyperopia <2.50 D, anisometropia <1.50 D) or ocular abnormalities. The VMI and VMIp were administered twice, on separate days. All VMI tests were scored by two trained scorers, and a subset of 50 tests was also scored by an experienced scorer. Scorers strictly applied objective scoring criteria. Analyses included interrater and test-retest assessments of bias, 95% limits of agreement, and intraclass correlation analysis. RESULTS: Trained scorers had no significant scoring bias compared with the experienced scorer. One of the two trained scorers tended to provide higher scores than the other (mean difference in standardized scores = 1.54). Interrater correlations were strong (0.75 to 0.88). VMI and VMIp test-retest comparisons indicated no significant bias (subjects did not tend to score better on retest). Test-retest correlations were moderate (0.54 to 0.58). The 95% limits of agreement for the VMI were -24.14 to 24.67 (scorer 1) and -26.06 to 26.58 (scorer 2), and the 95% limits of agreement for the VMIp were -27.11 to 27.34. CONCLUSIONS: The 95% limit of agreement for test-retest differences will be useful for determining if the VMI and VMIp have sufficient sensitivity for detecting change with treatment in both clinical and research settings. Further research on test-retest reliability reporting 95% limits of agreement for children across different age ranges is recommended, particularly if the test is to be used to detect changes due to intervention or treatment.
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Desenvolvimento Infantil/fisiologia , Testes Neuropsicológicos/normas , Desempenho Psicomotor/fisiologia , Percepção Visual/fisiologia , Adolescente , Criança , Feminino , Humanos , Aprendizagem/fisiologia , Masculino , Reprodutibilidade dos TestesRESUMO
PURPOSE: To compare oral reading fluency (ORF) in students with no/low astigmatism and moderate/high astigmatism and to assess the impact of spectacle correction on ORF in moderate and high astigmats. METHODS: Subjects were third- to eighth-grade students from a highly astigmatic population. Refractive error was determined through subjectively refined cycloplegic autorefraction. Data from students with ocular abnormalities, anisometropia, symptomatic binocular vision disorders, or refractive error that did not meet study criteria (no/low [cylinder < 1.00 both eyes, no significant myopia/hyperopia], moderate [cylinder ≥ 1.00 D both eyes, mean ≥ 1.00 D and < 3.00 D], or high astigmatism group [cylinder ≥ 1.00 D both eyes, mean ≥ 3.00 D]) were excluded. Oral reading fluency was tested with a modified version of the Dynamic Indicators of Basic Early Literacy Skills (DIBELS) Next test of ORF. No/low astigmats were tested without spectacles; astigmats were tested with and without spectacles. Mean ORF was compared in no/low astigmats and astigmats (with and without correction). Improvement in ORF with spectacles was compared between moderate and high astigmats. RESULTS: The sample included 130 no/low, 67 moderate, and 76 high astigmats. ORF was lower in uncorrected astigmats than in no/low astigmats (p = 0.011). ORF did not significantly differ in no/low astigmats and corrected astigmats (p = 0.10). ORF significantly improved with spectacle correction in high astigmats (p = 0.001; mean improvement, 6.55 words per minute) but not in moderate astigmats (p = 0.193; mean improvement, 1.87 words per minute). Effects of spectacle wear were observed in students who read smaller text stimuli (older grades). CONCLUSIONS: ORF is significantly reduced in students with bilateral astigmatism (≥1.00D) when uncorrected but not when best-corrected compared with their nonastigmatic peers. Improvement in ORF with spectacle correction is seen in high astigmats but not in moderate astigmats. These data support the recommendation for full-time spectacle wear in astigmatic students, particularly those with high astigmatism.
Assuntos
Astigmatismo/fisiopatologia , Leitura , Distúrbios da Fala/fisiopatologia , Astigmatismo/terapia , Criança , Óculos , Feminino , Humanos , Masculino , Miopia/fisiopatologia , Miopia/terapia , Percepção da Fala/fisiologia , Acuidade Visual/fisiologiaRESUMO
History A 56-year-old woman presented to the emergency department after a cross-country flight. While in flight, she experienced sudden onset of epigastric and midsternal chest pain with shortness of breath. Her symptoms improved markedly after she received oxygen on board, and she finished the flight without further incident. Once home later that night, the pain recurred, and she was taken to the hospital. Her history included chronic pain syndrome, hypertension, and refractory paroxysmal atrial fibrillation, for which she had undergone radiofrequency ablation on two occasions. Her most recent ablation was 1 month prior. Upon arrival in the emergency department, her vital signs were within normal limits, and an electrocardiogram was unchanged from baseline. A chest radiograph obtained at the time of physical examination was unchanged from baseline. Given her recent travel history, there was suspicion for a pulmonary embolism. Ventilation-perfusion imaging and lower extremity Doppler ultrasonography were performed (images not shown) and revealed no evidence of pulmonary embolism or lower extremity thrombus. Because of the patient's clinical stability and because her symptoms had improved, she declined admission for observation and returned home against medical advice. The patient returned to the emergency department 2 days later in severe distress, with unstable vital signs, a jaundiced appearance, and substantial pain in her chest and abdomen. Her creatinine level was 4.4 mg/dL (388.9 µmol/L) (increased from 0.9 mg/dL [79.6 µmol/L] 2 days prior). Frontal and lateral radiographs of the chest were obtained and indicated increasing pericardial effusion. Bedside echocardiography enabled confirmation of these radiographic findings, and pericardiocentesis was performed. The patient's condition immediately improved, and she was admitted to the cardiac intensive care unit. Her symptoms recurred 3 days later, and a pericardial drain was placed. Fluid cultures were preliminarily positive for enterococcus and gram-negative rods. After drain placement, she was scheduled for definitive treatment of recurrent symptomatic effusion. The preoperative work-up included a water-soluble contrast material-enhanced (iodixanol, 320 mg of iodine per milliliter) esophagram with computed tomography (CT) of the chest performed immediately thereafter.
Assuntos
Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Ablação por Cateter/efeitos adversos , Doenças do Esôfago/etiologia , Cardiopatias/etiologia , Pericárdio , Fístula do Sistema Respiratório/etiologia , Procedimentos Cirúrgicos Cardíacos/métodos , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
BACKGROUND: Tuberous sclerosis complex (TSC) predisposes to the development of benign lesions within multiple organ systems, including the brain, kidneys, heart, lungs, and skin. Disease mortality is due to space-occupying subependymal giant cell astrocytomas and hemorrhage-prone renal angiomyolipomas. The recent use of mTORC1 inhibitors, such as everolimus, has allowed for direct targeting of TSC-associated mass lesions without apparent effect on surrounding tissues. Because of the mechanism of these drugs, there is reason to believe that these effects are not durable and that there may be need for continued long-term maintenance therapy. CASE-DIAGNOSIS/TREATMENT: We present a case of TSC-associated mass lesions that were ill-suited for definitive surgical therapy. The patient was started on everolimus, however due to a complex social situation treatment was discontinued and ultimately resumed many months later. Radiologic studies acquired before and after each period of therapeutic onset/cessation reveal the dramatic but impermanent effects of mTORC1 inhibition. CONCLUSIONS: While everolimus provides a non-invasive way to treat TSC-associated lesions, patients may require lifelong therapy. When termination of therapy is considered, the patient should be made aware of the expectation of potentially dramatic increases in lesion size. If consideration is to be given to definitive surgical therapy, it should be pursued while the patient is still on the medication, or at least soon after treatment is halted.
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Imunossupressores/uso terapêutico , Sirolimo/análogos & derivados , Esclerose Tuberosa/tratamento farmacológico , Adolescente , Everolimo , Humanos , Masculino , Sirolimo/uso terapêutico , Esclerose Tuberosa/patologia , Esclerose Tuberosa/fisiopatologiaRESUMO
PURPOSE: This article provides recommendations for screening children aged 36 to younger than 72 months for eye and visual system disorders. The recommendations were developed by the National Expert Panel to the National Center for Children's Vision and Eye Health, sponsored by Prevent Blindness, and funded by the Maternal and Child Health Bureau of the Health Resources and Services Administration, United States Department of Health and Human Services. The recommendations describe both best and acceptable practice standards. Targeted vision disorders for screening are primarily amblyopia, strabismus, significant refractive error, and associated risk factors. The recommended screening tests are intended for use by lay screeners, nurses, and other personnel who screen children in educational, community, public health, or primary health care settings. Characteristics of children who should be examined by an optometrist or ophthalmologist rather than undergo vision screening are also described. RESULTS: There are two current best practice vision screening methods for children aged 36 to younger than 72 months: (1) monocular visual acuity testing using single HOTV letters or LEA Symbols surrounded by crowding bars at a 5-ft (1.5 m) test distance, with the child responding by either matching or naming, or (2) instrument-based testing using the Retinomax autorefractor or the SureSight Vision Screener with the Vision in Preschoolers Study data software installed (version 2.24 or 2.25 set to minus cylinder form). Using the Plusoptix Photoscreener is acceptable practice, as is adding stereoacuity testing using the PASS (Preschool Assessment of Stereopsis with a Smile) stereotest as a supplemental procedure to visual acuity testing or autorefraction. CONCLUSIONS: The National Expert Panel recommends that children aged 36 to younger than 72 months be screened annually (best practice) or at least once (accepted minimum standard) using one of the best practice approaches. Technological updates will be maintained at http://nationalcenter.preventblindness.org.
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Erros de Refração/diagnóstico , Transtornos da Visão/diagnóstico , Seleção Visual/normas , Criança , Pré-Escolar , Percepção de Profundidade/fisiologia , Feminino , Humanos , Masculino , Optometria , Erros de Refração/fisiopatologia , Sensibilidade e Especificidade , Transtornos da Visão/fisiopatologia , Seleção Visual/métodos , Acuidade Visual/fisiologiaRESUMO
PURPOSE: To evaluate and refine a newly developed instrument, the Student Refractive Error and Eyeglasses Questionnaire (SREEQ), designed to measure the impact of uncorrected and corrected refractive error on vision-related quality of life (VRQoL) in school-aged children. METHODS: A 38-statement instrument consisting of two parts was developed: part A relates to perceptions regarding uncorrected vision and part B relates to perceptions regarding corrected vision and includes other statements regarding VRQoL with spectacle correction. The SREEQ was administered to 200 Native American 6th- through 12th-grade students known to have previously worn and who currently require eyeglasses. Rasch analysis was conducted to evaluate the functioning of the SREEQ. Statements on parts A and B were analyzed to examine the dimensionality and constructs of the questionnaire, how well the items functioned, and the appropriateness of the response scale used. RESULTS: Rasch analysis suggested two items be eliminated and the measurement scale for matching items be reduced from a four-point response scale to a three-point response scale. With these modifications, categorical data were converted to interval-level data to conduct an item and person analysis. A shortened version of the SREEQ was constructed with these modifications, the SREEQ-R, which included the statements that were able to capture changes in VRQoL associated with spectacle wear for those with significant refractive error in our study population. CONCLUSIONS: Although part B of the SREEQ appears to have a less-than-optimal reliability to assess the impact of spectacle correction on VRQoL in our student population, it is able to detect statistically significant differences from pretest to posttest on both the group and individual levels to show that the instrument can assess the impact that glasses have on VRQoL. Further modifications to the questionnaire, such as those included in the SREEQ-R, could enhance its functionality.
Assuntos
Óculos , Qualidade de Vida/psicologia , Erros de Refração/psicologia , Erros de Refração/terapia , Perfil de Impacto da Doença , Inquéritos e Questionários , Adolescente , Criança , Avaliação da Deficiência , Feminino , Humanos , Indígenas Norte-Americanos , Masculino , Erros de Refração/etnologia , Estudantes , Acuidade Visual/fisiologia , Adulto JovemRESUMO
Abnormal movement patterns have been identified as important prospective risk factors for lower extremity injury, including anterior cruciate ligament injury. Specifically, poor neuromuscular control during the early landing phase has been associated with increased injury risk. Although it is commonly assumed that higher division collegiate athletes generally exhibit better movement patterns than lower division athletes, few studies compare the biomechanical differences on basic tasks such as jump landing between various levels of athletic groups. The objective of this study was to evaluate jump-landing and fitness differences among college-aged Intramural, Competitive Club, and National Collegiate Athletic Association (NCAA) Division I level athletes. Two hundred seventy-seven student-athletes (222 men, 55 women; age 19.3 ± 0.8 years) categorized as NCAA Division I, Competitive Club, or Intramural level athletes were evaluated during a jump-landing task using the Landing Error Scoring System (LESS), a validated qualitative movement assessment. Fitness was measured using the Army Physical Fitness Test (APFT). Results showed no significant differences in landing errors between the levels of athletic group (F(2,267) = 0.36, p = 0.70). There was a significant difference in landing errors between genders (F(1,268) = 3.99, p = 0.05). Significant differences in APFT scores were observed between level of athletic group (F(2,267) = 11.14, p < 0.001) and gender (F(1,268) = 9.27, p = 0.003). There was no significant correlation between the APFT and LESS scores (p = 0.26). In conclusion, higher level athletes had better physical fitness as measured by the APFT but did not as a group exhibit better landing technique. The implications of this research suggest that "high-risk" movement patterns are prevalent in all levels of athletes.
Assuntos
Lesões do Ligamento Cruzado Anterior , Traumatismos em Atletas/etiologia , Traumatismos em Atletas/fisiopatologia , Traumatismos do Joelho/etiologia , Educação Física e Treinamento/métodos , Aptidão Física/fisiologia , Esportes/fisiologia , Traumatismos em Atletas/prevenção & controle , Fenômenos Biomecânicos , Feminino , Humanos , Traumatismos do Joelho/prevenção & controle , Masculino , Militares , Movimento , Estudos Prospectivos , Estresse Mecânico , Estados Unidos , Adulto JovemRESUMO
PURPOSE: To describe change in spherical equivalent (M) in a longitudinal sample of Tohono O'odham students ages 3 to 18 years and to test the hypothesis that astigmatism creates complex cues to emmetropization, resulting in increased change in M in the direction of increasing myopia and increased occurrence of myopia. METHODS: Subjects were 777 Tohono O'odham Native American children on whom cycloplegic right eye autorefraction was measured on at least two study encounters between ages 3 and 18 years (first encounter prior to age 5.5 years, final encounter ≥3 years later). Regression lines were fit to individual subjects' longitudinal M data to estimate rate of change in M (regression slope, D/yr). Regression was also used to predict if a subject would be myopic (≤-0.75 D M) by age 18 years. Analysis of covariance was used to assess the relation between M slope and magnitude of baseline M and astigmatism. Chi-square analyses were used to assess the relation between predicted myopia onset and magnitude of baseline M and astigmatism. RESULTS: Mean M slope was significantly more negative for hyperopes (M ≥ +2.00) than for myopes (M ≤ -0.75) or for subjects neither hyperopic nor myopic (NHM, M > -0.75 and < +2.00), but there was no significant difference between the myopic and NHM groups. Chi-square analysis indicated that final myopia status varied across level of baseline astigmatism. Subjects with high astigmatism were more likely to be predicted to have significant myopia by age 18 years. CONCLUSIONS: The association between greater shift in M towards myopia with age in subjects who were hyperopic at baseline is consistent with continued emmetropization in the school years. Results regarding predicted myopia development imply that degradation of image quality due to refractive astigmatism creates complex cues to emmetropization, resulting in increased occurrence of myopia.
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Astigmatismo/fisiopatologia , Indígenas Norte-Americanos , Miopia/fisiopatologia , Adolescente , Arizona/epidemiologia , Astigmatismo/etnologia , Criança , Pré-Escolar , Sinais (Psicologia) , Emetropia/fisiologia , Feminino , Humanos , Estudos Longitudinais , Masculino , Midriáticos/administração & dosagem , Miopia/etnologia , Pupila/efeitos dos fármacos , Refração Ocular/fisiologiaRESUMO
BACKGROUND: Orofacial clefts are common worldwide and result from insufficient growth and/or fusion during the genesis of the derivatives of the first pharyngeal arch and the frontonasal prominence. Recent studies in mice carrying conditional and tissue-specific deletions of the human ortholog Dicer1, an RNAse III family member, have highlighted its importance in cell survival, differentiation, proliferation, and morphogenesis. Nevertheless, information regarding Dicer1 and its dependent microRNAs (miRNAs) in mammalian palatogenesis and orofacial development is limited. AIMS: To describe the craniofacial phenotype, gain insight into potential mechanisms underlying the orofacial defects in the Pax2-Cre/Dicer1 CKO mouse, and shed light on the role of Dicer1 in mammalian palatogenesis. MATERIALS AND METHODS: Histological and molecular assays of wild type (WT) and Pax2-Cre/Dicer1(loxP/loxP) (Dicer1 CKO) mice dissected tissues have been performed to characterize and analyze the orofacial dysmorphism in Pax2-Cre/Dicer1(loxP/loxP) mouse. RESULTS: Dicer1 CKO mice exhibit late embryonic lethality and severe craniofacial dysmorphism, including a secondary palatal cleft. Further analysis suggest that Dicer1 deletion neither impacts primary palatal development nor the initial stages of secondary palatal formation. Instead, Dicer1 is implicated in growth, differentiation, mineralization, and survival of cells in the lateral palatal shelves. Histological and molecular analysis demonstrates that secondary palatal development becomes morphologically arrested prior to mineralization around E13.5 with a significant increase in the expression levels of apoptotic markers (P < 0.01). CONCLUSIONS: Pax2-Cre-mediated Dicer1 deletion disrupts lateral palatal outgrowth and bone mineralization during palatal shelf development, therefore providing a mammalian model for investigating the role of miRNA-mediated signaling pathways during palatogenesis.
RESUMO
Purpose: To assess the feasibility of using a thermal microsensor to monitor spectacle wear in infants and toddlers, to determine the inter-method reliability of two methods of estimating spectacle wear from sensor data, and to validate sensor estimates of wear. Methods: Fourteen children, 3 to <48 months of age, and one adult were provided pediatric spectacles containing their spectacle prescription. A thermal microsensor attached to the spectacle headband recorded date, time, and ambient temperature every 15 minutes for 14 days. Parents were asked for daily spectacle wear reports, and the adult recorded wear using a smartphone app. Sensor data were dichotomized (wear/non-wear) using two methods: temperature threshold (TT) and human judgment (HJ). Kappa statistics assessed inter-method reliability (child data) and accuracy (adult data). Results: Data from two child participants were excluded (one because of corrupted sensor data and the other because of no parent log data). Sensor data were collected more reliably than parent wear reports. The TT and HJ analysis of child data yielded similar reliability. Adult sensor data scored using the HJ method provided more valid estimates of wear than the TT method (κ = 0.94 vs. 0.78). Conclusions: We have demonstrated that it is feasible to deduce periods of spectacle wear using a thermal data logger and that the sensor is tolerated by children. Translational Relevance: Results indicate that it is feasible to use a thermal microsensor to measure spectacle wear for use in clinical monitoring or for research on spectacle treatment in children under 4 years of age.
Assuntos
Erros de Refração , Dispositivos Eletrônicos Vestíveis , Adulto , Criança , Pré-Escolar , Óculos , Humanos , Lactente , Pais , Reprodutibilidade dos TestesRESUMO
INTRODUCTION: Transgender and nonbinary peoplehave been identified as vulnerable and clinically underserved and experience health disparities. Lack of health care provider knowledge about transgender and gender diverse populations is a barrier to care, impacting health outcomes. The aim of this project was to develop, implement, and evaluate a simulation learning activity for midwifery and women's health nurse practitioner students and obstetrics and gynecology residents to interact with transgender and nonbinary individuals, with the goal of enhancing health history taking comfort and skills. METHODS: A partnership was formed among University faculty and simulation educators, a community clinic providing gender-affirming care, and members of transgender and gender diverse populations who served as patient-teachers. Two cases frequently encountered in clinics providing care to transgender individuals were developed for the simulation. Learners were divided into interprofessional groups of 3 and completed one of 2 case scenarios with a patient-teacher. Learners and patient-teachers debriefed after the simulation to discuss and reflect on the experience. RESULTS: Thirty-three learners participated in the simulation, 12 midwifery students, 16 women's health nurse practitioner students and 5 obstetrics and gynecology residents. Significant differences were observed for all comfort and skills questions, showing increased perceived comfort and skills from pre- to postsimulation. There were no significant differences in attitude responses. DISCUSSION: We successfully created and implemented a new sexual and reproductive history taking skills simulation in partnership with community clinic staff and transgender and nonbinary persons. The session was well received by learners and patient-teachers. Learners demonstrated significant improvements in comfort and skills in history taking in this setting and provided favorable feedback about the experience. This simulation can serve as a guide to others providing education to future midwives, women's health nurse practitioners, and obstetrician-gynecologists.
Assuntos
Pessoas Transgênero , Humanos , UniversidadesRESUMO
BACKGROUND/PURPOSE: Abdominal lymphatic malformations (LM) are a rare subset of vascular anomaly caused by abnormal development of the lymphatic system. They are classified as macrocystic, microcystic or combination macrocystic and microcystic. Surgical resection, percutaneous sclerotherapy, and medical therapy are all employed to treat these complex and often symptomatic lesions. No standardized treatment algorithm exists currently. The purpose of this study was to establish a multidisciplinary treatment approach to abdominal LMs. METHODS: A retrospective observational study was conducted from 2013 to 2019 on patients with abdominal LMs at a single tertiary children's hospital vascular anomalies center. Demographics, imaging, and treatment modality were recorded. Clinical and/or radiographic response to the primary treatment modality as well as complications was the outcomes measured. RESULTS: Nineteen patients (12 macrocystic, 5 microcystic and 2 combined) were identified, with a median age at diagnosis of 2.2â¯years (range 0.1-20.8â¯years). Sclerotherapy was the most common primary treatment, followed by surgical resection and sirolimus. No difference in clinical response (pâ¯=â¯0.58) or complications (pâ¯=â¯0.31) was observed based on primary treatment or subtypes. CONCLUSIONS: Based on our institutional experience, we propose an LM subtype-based treatment algorithm for abdominal LMs. It employs a multidisciplinary approach, and results in satisfactory patient outcomes with minimal complications. LEVEL OF EVIDENCE: Level III, retrospective comparative study.
Assuntos
Anormalidades Linfáticas , Abdome , Adolescente , Adulto , Criança , Pré-Escolar , Humanos , Lactente , Anormalidades Linfáticas/diagnóstico por imagem , Anormalidades Linfáticas/terapia , Estudos Retrospectivos , Escleroterapia , Resultado do Tratamento , Adulto JovemRESUMO
PURPOSE: To determine whether reduced astigmatism-corrected acuity for vertical (V) and/or horizontal (H) gratings and/or meridional amblyopia (MA) are present before 3 years of age in children who have with-the-rule astigmatism. METHODS: Subjects were 448 children, 6 months through 2 years of age with no known ocular abnormalities other than with-the-rule astigmatism, who were recruited through Women, Infants and Children clinics on the Tohono O'odham reservation. Children were classified as non-astigmats (< or =2.00 diopters) or astigmats (>2.00 diopters) based on right eye non-cycloplegic autorefraction measurements (Welch Allyn SureSight). Right eye astigmatism-corrected grating acuity for V and H stimuli was measured using the Teller Acuity Card procedure while children wore cross-cylinder lenses to correct their astigmatism or plano lenses if they had no astigmatism. RESULTS: Astigmatism-corrected acuity for both V and H gratings was significantly poorer in the astigmats than in the non-astigmats, and the reduction in acuity for astigmats was present for children in all three age groups examined (6 months to <1 year, 1 to <2 years, and 2 to <3 years). There was no significant difference in V-H grating acuity (no evidence of MA) for the astigmatic group as a whole, or when data were analyzed for each age group. CONCLUSIONS: Even in the youngest age group, astigmats tested with astigmatism correction showed reduced acuity for both V and H gratings, which suggests that astigmatism is having a negative influence on visual development. We found no evidence of orientation-related differences in astigmatism-corrected grating acuity, indicating either that MA does not develop before 3 years of age, or that most of the astigmatic children had a type of astigmatism, i.e., hyperopic, that has proven to be less likely than myopic or mixed astigmatism to result in MA.
Assuntos
Ambliopia/etiologia , Astigmatismo/complicações , Óculos , Refração Ocular/fisiologia , Ambliopia/fisiopatologia , Ambliopia/reabilitação , Astigmatismo/fisiopatologia , Astigmatismo/reabilitação , Pré-Escolar , Progressão da Doença , Feminino , Seguimentos , Humanos , Lactente , Masculino , Prognóstico , Estudos Retrospectivos , Acuidade Visual/fisiologiaRESUMO
PURPOSE: To describe the prevalence of high astigmatism in infants and young children who are members of a Native American tribe with a high prevalence of astigmatism. METHODS: SureSight autorefraction measurements were obtained for 1461 Tohono O'odham children aged 6 months to 8 years. RESULTS: The prevalence of astigmatism >2.00 diopters was 30% in Tohono O'odham children during infancy (6 months to <1 year of age) and was 23 to 29% at ages 2 to 7 years. However, prevalence dipped to 14% in children 1 to <2 years of age. At all ages, axis of astigmatism was with-the-rule (plus cylinder axis 90 degrees +/- 30 degrees ) in at least 94% of cases. CONCLUSIONS: As in non-Native American populations, Tohono O'odham infants show a high prevalence of astigmatism, which decreases in the second year of life. However, the prevalence of high astigmatism in Tohono O'odham children increases by age 2 to <3 years to a level near that seen in infancy and remains at that level until at least age 8 years. Longitudinal data are needed to determine whether the increase in high astigmatism after infancy occurs in infants who had astigmatism as infants or is due to the development of high astigmatism in children who did not show astigmatism during infancy.
Assuntos
Astigmatismo/epidemiologia , Indígenas Norte-Americanos/estatística & dados numéricos , Fatores Etários , Arizona/epidemiologia , Criança , Pré-Escolar , Humanos , Lactente , Estudos Longitudinais , Prevalência , Testes VisuaisRESUMO
We describe a set of distance and near, adult and child, visual acuity tests for home use. The five charts are packaged in a PDF document and are also available as JPEG images that can be printed on standard letter paper or displayed on a monitor or handheld device. Adult distance visual acuity is tested using a modified ETDRS Chart R; child distance vision is tested using a similarly formatted HOTV logMAR chart. Testing distance is 5 or 10 feet, appropriate for home use. Near visual acuity is displayed in the range of J16 to J1 using random words (for adults) or in HOTV matching format (for young children). An Amsler Grid and HOTV matching card are included. The charts include a calibration circle. For those without a printer, sending a JPEG image as an email attachment initiates onscreen testing with a single click. Devices with smaller screens require an assistant to scroll through the display. The test can performed without assistance from a printed page.