Detalhe da pesquisa
1.
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.
N Engl J Med
; 387(12): 1099-1110, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36129998
2.
Protective Effects of Lovastatin in a Population-Based ALS Study and Mouse Model.
Ann Neurol
; 93(5): 881-892, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627836
3.
Acute Trem2 reduction triggers increased microglial phagocytosis, slowing amyloid deposition in mice.
Proc Natl Acad Sci U S A
; 118(27)2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34187891
4.
Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.
N Engl J Med
; 383(10): 919-930, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877582
5.
Lumbar punctures are safe in patients with ALS and have a risk profile similar to that in the non-ALS population.
Muscle Nerve
; 68(5): 771-775, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37566385
6.
Specific RNA interactions promote TDP-43 multivalent phase separation and maintain liquid properties.
EMBO Rep
; 22(12): e53632, 2021 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34787357
7.
A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues.
Proc Natl Acad Sci U S A
; 117(18): 10003-10014, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32300008
8.
Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial.
J Neurol Neurosurg Psychiatry
; 2022 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35577511
9.
Incidence of amyotrophic lateral sclerosis in older adults.
Muscle Nerve
; 66(3): 289-296, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35678083
10.
Smartphone data during the COVID-19 pandemic can quantify behavioral changes in people with ALS.
Muscle Nerve
; 63(2): 258-262, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33118628
11.
Long-term survival of participants in the CENTAUR trial of sodium phenylbutyrate-taurursodiol in amyotrophic lateral sclerosis.
Muscle Nerve
; 63(1): 31-39, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33063909
12.
Amyotrophic lateral sclerosis care and research in the United States during the COVID-19 pandemic: Challenges and opportunities.
Muscle Nerve
; 62(2): 182-186, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32445195
13.
Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis.
Brain
; 141(9): 2561-2575, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30007309
14.
MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models.
J Neurosci
; 37(22): 5574-5586, 2017 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28416596
15.
MicroRNA signature of central nervous system-infiltrating dendritic cells in an animal model of multiple sclerosis.
Immunology
; 155(1): 112-122, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29749614
16.
Poly-dipeptides encoded by the C9ORF72 repeats block global protein translation.
Hum Mol Genet
; 25(9): 1803-13, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26931465
17.
Emerging antisense oligonucleotide and viral therapies for amyotrophic lateral sclerosis.
Curr Opin Neurol
; 31(5): 648-654, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30028737
18.
Phosphorylated neurofilament heavy chain: A biomarker of survival for C9ORF72-associated amyotrophic lateral sclerosis.
Ann Neurol
; 82(1): 139-146, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28628244
19.
CK-2127107 amplifies skeletal muscle response to nerve activation in humans.
Muscle Nerve
; 57(5): 729-734, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29150952
20.
Defining SOD1 ALS natural history to guide therapeutic clinical trial design.
J Neurol Neurosurg Psychiatry
; 88(2): 99-105, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27261500