Detalhe da pesquisa
1.
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review.
Molecules
; 29(9)2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38731421
2.
Historical perspective of tumor glycolysis: A century with Otto Warburg.
Semin Cancer Biol
; 86(Pt 2): 325-333, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35809880
3.
Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma.
Int J Mol Sci
; 24(9)2023 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175477
4.
New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy.
J Enzyme Inhib Med Chem
; 37(1): 145-150, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34894990
5.
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives.
Molecules
; 27(19)2022 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36235072
6.
The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies.
Semin Cancer Biol
; 60: 238-248, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31445217
7.
Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds.
Br J Cancer
; 123(4): 644-656, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32493992
8.
Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study.
Molecules
; 26(1)2020 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375358
9.
First Examples of H2S-Releasing Glycoconjugates: Stereoselective Synthesis and Anticancer Activities.
Bioconjug Chem
; 30(3): 614-620, 2019 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30609890
10.
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.
J Enzyme Inhib Med Chem
; 34(1): 589-596, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30696302
11.
Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents.
Molecules
; 24(19)2019 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31569409
12.
Effect of Tumor Relevant Acidic Environment in the Interaction of a N-hydroxyindole-2-Carboxylic Derivative with the Phospholipid Bilayer.
Pharm Res
; 35(9): 175, 2018 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29987655
13.
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors.
J Enzyme Inhib Med Chem
; 33(1): 956-961, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29747534
14.
Risks and benefits related to alimentary exposure to xenoestrogens.
Crit Rev Food Sci Nutr
; 57(16): 3384-3404, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26744831
15.
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors.
Bioorg Med Chem Lett
; 27(21): 4812-4816, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28993050
16.
Constituents of Polygala flavescens ssp. flavescens and Their Activity as Inhibitors of Human Lactate Dehydrogenase.
J Nat Prod
; 80(7): 2077-2087, 2017 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28692289
17.
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors.
J Enzyme Inhib Med Chem
; 32(1): 1240-1252, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28936880
18.
Three-Dimensional Analysis of the Interactions between hLDH5 and Its Inhibitors.
Molecules
; 22(12)2017 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29236080
19.
Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance.
Haematologica
; 106(4): 1163-1166, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32554563
20.
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors.
J Enzyme Inhib Med Chem
; 31(1): 137-46, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-25669350