Detalhe da pesquisa
1.
In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1.
Drug Metab Dispos
; 45(2): 137-144, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27895114
2.
Amount of Testosterone on Laundered Clothing After Use of Testosterone Topical 2% Solution by Healthy Male Volunteers.
J Sex Med
; 13(2): 187-93, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26803453
3.
Considerations for assessing the potential effects of antidiabetes drugs on cardiac ventricular repolarization: A report from the Cardiac Safety Research Consortium.
Am Heart J
; 170(1): 23-35, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26093861
4.
Effect of pomaglumetad methionil on the QT interval in subjects with schizophrenia.
Int J Clin Pharmacol Ther
; 53(6): 462-70, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25881753
5.
Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects.
J Clin Psychopharmacol
; 34(1): 9-16, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24346757
6.
Effect of deodorant and antiperspirant use and presence or absence of axillary hair on absorption of testosterone 2% solution applied to men's axillae.
J Sex Med
; 11(11): 2809-17, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25123988
7.
Disposition and metabolism of LY2603618, a Chk-1 inhibitor following intravenous administration in patients with advanced and/or metastatic solid tumors.
Xenobiotica
; 44(9): 827-41, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24666335
8.
Modeling and simulations to confirm a controlled hypoglycemic stress test in healthy subjects is not associated with clinically significant QT prolongations.
Int J Clin Pharmacol Ther
; 52(9): 717-25, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24887333
9.
Evaluation of the effects of duloxetine and escitalopram on 24-hour heart rate variability: a mechanistic study using heart rate variability as a pharmacodynamic measure.
J Clin Psychopharmacol
; 33(2): 236-9, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23422380
10.
Effects of atomoxetine on the QT interval in healthy CYP2D6 poor metabolizers.
Br J Clin Pharmacol
; 75(2): 538-49, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22803597
11.
The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor.
Eur J Clin Pharmacol
; 69(12): 2011-9, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23955175
12.
Evaluation of methods for achieving stable INR in healthy subjects during a multiple-dose warfarin study.
Eur J Clin Pharmacol
; 68(3): 239-47, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21881887
13.
Effect of exenatide on the pharmacokinetics of a combination oral contraceptive in healthy women: an open-label, randomised, crossover trial.
BMC Clin Pharmacol
; 12: 8, 2012 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22429273
14.
Systematic decrements in QTc between the first and second day of contiguous daily ECG recordings under controlled conditions.
Pacing Clin Electrophysiol
; 34(9): 1116-27, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21535038
15.
Post-injection delirium/sedation syndrome in patients with schizophrenia treated with olanzapine long-acting injection, II: investigations of mechanism.
BMC Psychiatry
; 10: 45, 2010 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20537130
16.
Pharmacokinetic interaction between tadalafil and bosentan in healthy male subjects.
J Clin Pharmacol
; 48(5): 610-8, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18305126
17.
Hemodynamic interaction between a daily dosed phosphodiesterase 5 inhibitor, tadalafil, and the alpha-adrenergic blockers, doxazosin and tamsulosin, in middle-aged healthy male subjects.
J Clin Pharmacol
; 47(10): 1303-10, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17906163
18.
The combined use of ibutilide as an active control with intensive electrocardiographic sampling and signal averaging as a sensitive method to assess the effects of tadalafil on the human QT interval.
J Am Coll Cardiol
; 46(4): 678-87, 2005 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16098435
19.
Relative bioavailability of three formulations of galunisertib administered as monotherapy in patients with advanced or metastatic cancer.
Drugs Context
; 5: 212303, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27990167
20.
Evaluation of the effect of necitumumab on the corrected QT interval in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 78(2): 271-80, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27312733