Wide-Angle Beam Steering Closed-Form Pillbox Antenna Fed by Substrate-Integrated Waveguide Horn for On-the-Move Satellite Communications.

Wide-angle mechanical beam steering for on-the-move satellite communications is presented in this paper based on a closed-form pillbox antenna system. It includes three main parts: a fixed-feed part, which is a substrate-integrated waveguide (SIW) horn with an extended aperture attached to a parabolic reflector; a novel quasi-optical system, which is a single coupling slot alongside and without spacing from the parabolic reflector; and a radiating disc, which is a leaky-wave metallic pattern. To make the antenna compact, pillbox-based feeding is implemented underneath the metallic patterns. The antenna is designed based on a substrate-guided grounded concept using leaky-wave metallic patterns operating at 20 GHz. Beam scanning is achieved using mechanical rotation of the leaky-wave metallic patterns. The proposed antenna has an overall size of 340 × 335 × 2 mm3, a gain of 23.2 dBi, wide beam scanning range of 120°, from -60° to +60° in the azimuthal plane, and a low side lobe level of -17.8 dB at a maximum scan angle of 60°. The proposed antenna terminal is suitable for next-generation ubiquitous connectivity for households and small businesses in remote areas, ships, unmanned aerial vehicles, and disaster management.

The Progress of Glucose Monitoring-A Review of Invasive to Minimally and Non-Invasive Techniques, Devices and Sensors.

Current glucose monitoring methods for the ever-increasing number of diabetic people around the world are invasive, painful, time-consuming, and a constant burden for the household budget. The non-invasive glucose monitoring technology overcomes these limitations, for which this topic is significantly being researched and represents an exciting and highly sought after market for many companies. This review aims to offer an up-to-date report on the leading technologies for non-invasive (NI) and minimally-invasive (MI) glucose monitoring sensors, devices currently available in the market, regulatory framework for accuracy assessment, new approaches currently under study by representative groups and developers, and algorithm types for signal enhancement and value prediction. The review also discusses the future trend of glucose detection by analyzing the usage of the different bands in the electromagnetic spectrum. The review concludes that the adoption and use of new technologies for glucose detection is unavoidable and closer to become a reality.

Shielded Cone Coil Array for Non-Invasive Deep Brain Magnetic Stimulation.

Non-invasive deep brain stimulation using transcranial magnetic stimulation is a promising technique for treating several neurological disorders, such as Alzheimer's and Parkinson's diseases. However, the currently used coils do not demonstrate the required stimulation performance in deep regions of the brain, such as the hippocampus, due to the rapid decay of the field inside the head. This study proposes an array that uses the cone coil method for deep stimulation. This study investigates the impact of magnetic core and shielding on field strength, focality, decay rate, and safety. The coil's size and shape effects on the electric field distribution in deep brain areas are also examined. The finite element method is used to calculate the induced electric field in a realistic human head model. The simulation results indicate that the magnetic core and shielding increase the electric field intensity and enhance focality but do not improve the field decay rate. However, the decay rate can be reduced by increasing the coil size at the expense of focality. By adopting an optimum cone structure, the proposed five-coil array reduces the electric field attenuation rate to reach the stimulation threshold in deep regions while keeping all other regions within safety limits. In vitro and in vivo experimental results using a head phantom and a dead pig's head validate the simulated results and confirm that the proposed design is a reliable and efficient candidate for non-invasive deep brain magnetic stimulation.

Benign and Malignant Skin Lesions: Dielectric Characterization, Modelling and Analysis in Frequency Band 1 to 14 GHz.

OBJECTIVE: This paper aims to characterize Non-Melanoma malignancies and their corresponding benign conditions in ex-vivo/in-vivo tissue environments to study the feasibility of microwave techniques for skin cancer detection. METHODS: The dielectric dataset is developed across the frequency band 1 to 14 GHz using Keysight slim-form and RG405 probe characterization systems. The acquired reflection data captured by the systems is converted to dielectric values using the Open-Water-Short and Open-Water-Liquid calibration methods, respectively. Furthermore, the impact of anaesthesia application during skin excision procedure on ex-vivo dielectric data is investigated. RESULTS: The observations suggest that the dielectric properties (DPs) of excised skin lesions may not accurately represent actual tissue properties as they vary significantly (Dielectric Constant Contrast = 30.7%, Loss-Factor Contrast = 66.6%) compared to pre-excision conditions. In-vivo dielectric data analysis indicates that when compared to healthy skin, malignant Basal Cell Carcinoma presents increased DPs (dielectric constant & loss factor) of (24.8 & 38.6 %), respectively. On the other hand, for malignant Squamous Cell Carcinoma and pre-malignant Actinic Keratosis, the measured results show decreased DPs (dielectric constant & loss factor) accordingly by (19.4 & 18.2 %) and (19.2 & 27.9 %). The corresponding benign lesions have less than 13 % dielectric contrast compared to healthy skin across the tested band. CONCLUSION: The significant contrasts between in-vivo healthy and cancerous skin DPs strongly suggest the viability of the microwave band for skin cancer detection. SIGNIFICANCE: The research finding of this study would be critical in developing a portable electromagnetic system for skin cancer detection.

Implantable Sensor for Detecting Changes in the Loss Tangent of Cerebrospinal Fluid.

The increasing utilization of cerebrospinal fluid (CSF) in early detection of Alzheimer's disease (AD) is attributed to the change of Amyloid- ß proteins. Since, the brain is suspended in CSF, changes of Amyloid- ß proteins in CSF reflect a pathophysiological variation of the brain due to AD. However, the correlation between Amyloid- ß proteins and the dielectric properties (DPs) of CSF is still an open question. This paper reports the characterized DPs of CSF collected from canines using lumbar punctures. The CSF samples from canines show a strong correlation with respect to human in terms of the loss tangent, which indicates suitability of using canines as translational primates. Amyloid- ß [ Aß(1-40) and Aß(1-42)] proteins associated with AD were added to CSF samples in order to emulate AD condition. The results of emulated AD condition suggest a decrease in the relative permittivity and increase in the loss tangent. To detect changes in the loss tangent of CSF, which combines both relative permittivity and conductivity, a developed sensor is proposed. The designed sensor consists of a voltage controlled oscillator (VCO) and implantable antenna, which exhibits a wideband and low quality factor to be stable with respect to changes in the loss tangent of CSF. The measurements of the received power levels from the sensor in different liquid-based phantoms having different loss tangent values were used to correlate changes in the loss tangent. The developed correlation model is able to predict the loss tangent based on the received power level, which can be used to detect changes in the loss tangent of CSF due to AD. Consequently, this approach could be used as an early diagnosis of AD.

Millimeter-Wave Substrate Integrated Waveguide Probe for Skin Cancer Detection.

This article presents an efficient and low-cost near-field probe, designed for early-stage skin cancer detection. Thanks to a tapered section, the device can achieve a sharp concentration of electric field at its tip. Moreover, the adoption of substrate integrated waveguide (SIW) technology ensures an easy and cheap fabrication process. The probe is realized on a high dielectric constant substrate (Rogers RO3210) that provides a good impedance matching with the skin, thus allowing to use the device in direct contact with it. This feature is essential to ensure that the proposed system can be adopted as a practical and effective tool for a fast scanning of many suspected skin regions. The probe is designed to operate at around 40 GHz in order to achieve the penetration depth required to detect small cancer lumps in the skin, while preventing the fields from interacting with the underlying biological tissues. Furthermore, the concept of detection depth is defined with the goal of introducing a metric that is more suitable than the penetration depth to express the notion of the maximum distance from the skin surface at which a tumor can be detected. Thanks to a differential imaging algorithm, the probe is capable of working on every different skin types and body region. The proposed device has a lateral sensitivity and detection depth of 0.2 and 0.55 mm respectively. The probe was designed and tested through simulations in CST Microwave Studio, as well as fabricated and validated through measurements on an artificial human skin phantom.

Wearable Electromagnetic Head Imaging System Using Flexible Wideband Antenna Array Based on Polymer Technology for Brain Stroke Diagnosis.

Given the increased interest in a fast, portable, and on-spot medical diagnostic tool that enables early diagnosis for patients with brain stroke, a new approach of a wearable electromagnetic head imaging system based on the polymer material is proposed. A flexible low-profile, wideband, and unidirectional antenna array with electromagnetic band gap (EBG) and metamaterial (MTM) unit cells reflector is utilized. The designed antenna consists of a 4 × 4 radiating patch loaded with symmetrical extended open-ended U-slots and fed by combination of series and corporate transmission lines. A mushroom-like 10-EBG unit cell arrays are arranged around the feeding network to reduce surface waves, whereas 4 × 4 MTM unit cells are placed on the back-side of the antenna to enable unidirectional radiation. The antenna is designed and embedded on a multilayer low cost, low loss, transparent, and robust polymer poly-di-methyl-siloxane (PDMS) substrate and optimized to operate in contact with the human head. The simulated and measured results show that the antenna has a fractional bandwidth of 53.8% (1.16-1.94 GHz), more than 80% of radiation efficiency, and satisfactory field penetration in the head tissues with a safe specific absorption rate. An eight-element array is then configured on 300 × 360 × 4.1 mm3 PDMS material covering an average human head size and used as a worn part of the imaging system. A realistic-shaped 3-D specific anthropomorphic mannequin (SAM) head phantom is used to verify the performance of the designed array. The imaging results indicate the possibility of using the designed conformal array to detect a bleeding inside the brain using a confocal image algorithm.

On-site Rapid Diagnosis of Intracranial Hematoma using Portable Multi-slice Microwave Imaging System.

Rapid, on-the-spot diagnostic and monitoring systems are vital for the survival of patients with intracranial hematoma, as their conditions drastically deteriorate with time. To address the limited accessibility, high costs and static structure of currently used MRI and CT scanners, a portable non-invasive multi-slice microwave imaging system is presented for accurate 3D localization of hematoma inside human head. This diagnostic system provides fast data acquisition and imaging compared to the existing systems by means of a compact array of low-profile, unidirectional antennas with wideband operation. The 3D printed low-cost and portable system can be installed in an ambulance for rapid on-site diagnosis by paramedics. In this paper, the multi-slice head imaging system's operating principle is numerically analysed and experimentally validated on realistic head phantoms. Quantitative analyses demonstrate that the multi-slice head imaging system is able to generate better quality reconstructed images providing 70% higher average signal to clutter ratio, 25% enhanced maximum signal to clutter ratio and with around 60% hematoma target localization compared to the previous head imaging systems. Nevertheless, numerical and experimental results demonstrate that previous reported 2D imaging systems are vulnerable to localization error, which is overcome in the presented multi-slice 3D imaging system. The non-ionizing system, which uses safe levels of very low microwave power, is also tested on human subjects. Results of realistic phantom and subjects demonstrate the feasibility of the system in future preclinical trials.

Portable Wideband Microwave Imaging System for Intracranial Hemorrhage Detection Using Improved Back-projection Algorithm with Model of Effective Head Permittivity.

Intracranial hemorrhage is a medical emergency that requires rapid detection and medication to restrict any brain damage to minimal. Here, an effective wideband microwave head imaging system for on-the-spot detection of intracranial hemorrhage is presented. The operation of the system relies on the dielectric contrast between healthy brain tissues and a hemorrhage that causes a strong microwave scattering. The system uses a compact sensing antenna, which has an ultra-wideband operation with directional radiation, and a portable, compact microwave transceiver for signal transmission and data acquisition. The collected data is processed to create a clear image of the brain using an improved back projection algorithm, which is based on a novel effective head permittivity model. The system is verified in realistic simulation and experimental environments using anatomically and electrically realistic human head phantoms. Quantitative and qualitative comparisons between the images from the proposed and existing algorithms demonstrate significant improvements in detection and localization accuracy. The radiation and thermal safety of the system are examined and verified. Initial human tests are conducted on healthy subjects with different head sizes. The reconstructed images are statistically analyzed and absence of false positive results indicate the efficacy of the proposed system in future preclinical trials.