Detalhe da pesquisa
1.
Immune-infiltrated kidney organoid-on-chip model for assessing T cell bispecific antibodies.
Proc Natl Acad Sci U S A
; 120(35): e2305322120, 2023 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603766
2.
Renal reabsorption in 3D vascularized proximal tubule models.
Proc Natl Acad Sci U S A
; 116(12): 5399-5404, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833403
3.
Phase Ib study evaluating safety and clinical activity of the anti-HER3 antibody lumretuzumab combined with the anti-HER2 antibody pertuzumab and paclitaxel in HER3-positive, HER2-low metastatic breast cancer.
Invest New Drugs
; 36(5): 848-859, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29349598
4.
Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies.
Elife
; 102021 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378534
5.
Refining LNA safety profile by controlling phosphorothioate stereochemistry.
PLoS One
; 15(6): e0232603, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32530964
6.
Neutrophilic infiltration in organ-on-a-chip model of tissue inflammation.
Lab Chip
; 20(18): 3365-3374, 2020 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32761043
7.
Developing in vitro assays to transform gastrointestinal safety assessment: potential for microphysiological systems.
Lab Chip
; 20(7): 1177-1190, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32129356
8.
GalNAc Conjugation Attenuates the Cytotoxicity of Antisense Oligonucleotide Drugs in Renal Tubular Cells.
Mol Ther Nucleic Acids
; 14: 67-79, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30583097
9.
Mechanistic Investigations of Diarrhea Toxicity Induced by Anti-HER2/3 Combination Therapy.
Mol Cancer Ther
; 17(7): 1464-1474, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29654069
10.
BRCA1 can modulate RNA polymerase II carboxy-terminal domain phosphorylation levels.
Mol Cell Biol
; 24(16): 6947-56, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15282296
11.
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes.
Nat Commun
; 8(1): 262, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28811479
12.
Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling.
Mol Ther Nucleic Acids
; 6: 89-105, 2017 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28325303
13.
High levels of oxidative stress globally inhibit gene transcription and histone acetylation.
DNA Cell Biol
; 25(2): 124-34, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16460236
14.
Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips.
Sci Rep
; 6: 34845, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27725720
15.
Establishment of a Predictive In Vitro Assay for Assessment of the Hepatotoxic Potential of Oligonucleotide Drugs.
PLoS One
; 11(7): e0159431, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27442522
16.
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
Nat Cell Biol
; 17(1): 57-67, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25487280
17.
A TALEN genome-editing system for generating human stem cell-based disease models.
Cell Stem Cell
; 12(2): 238-51, 2013 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23246482
18.
The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification.
Dev Cell
; 20(5): 583-596, 2011 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21571217
19.
The BRCA1 COOH-terminal region acts as an RNA polymerase II carboxyl-terminal domain kinase inhibitor that modulates p21WAF1/CIP1 expression.
J Biol Chem
; 281(30): 21119-21130, 2006 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16735508