Detalhe da pesquisa
1.
Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Int J Mol Sci
; 22(6)2021 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33805843
2.
Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson's Disease.
Mol Ther
; 26(2): 550-567, 2018 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29273501
3.
Human α-synuclein overexpression in mouse serotonin neurons triggers a depressive-like phenotype. Rescue by oligonucleotide therapy.
Transl Psychiatry
; 12(1): 79, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210396
4.
Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys.
EBioMedicine
; 59: 102944, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32810825
5.
Corrigendum to "Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys" [EBioMedicine 2020; 59:102944].
EBioMedicine
; 74: 103731, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34852293
6.
Acute 5-HT1A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions.
Psychopharmacology (Berl)
; 225(1): 61-74, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22820867