Detalhe da pesquisa
1.
Cellular dormancy in minimal residual disease following targeted therapy.
Breast Cancer Res
; 23(1): 63, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34088357
2.
Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours.
Br J Cancer
; 125(1): 28-37, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941878
3.
PIK3CA mutant tumors depend on oxoglutarate dehydrogenase.
Proc Natl Acad Sci U S A
; 114(17): E3434-E3443, 2017 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28396387
4.
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.
Nature
; 462(7269): 108-12, 2009 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19847166
5.
Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.
Nat Cell Biol
; 9(5): 493-505, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17450133
6.
The transcriptional repressor Snail promotes mammary tumor recurrence.
Cancer Cell
; 8(3): 197-209, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16169465
7.
CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors.
bioRxiv
; 2023 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36778419
8.
CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors.
Sci Adv
; 9(47): eadg8876, 2023 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38000020
9.
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis.
Cancer Cell
; 2(6): 451-61, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12498714
10.
Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss.
J Clin Invest
; 118(1): 51-63, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18060046
11.
Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling.
Clin Cancer Res
; 27(1): 342-354, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33046519
12.
Safety and efficacy of nazartinib (EGF816) in adults with EGFR-mutant non-small-cell lung carcinoma: a multicentre, open-label, phase 1 study.
Lancet Respir Med
; 8(6): 561-572, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31954624
13.
SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors.
Mol Cancer Ther
; 18(7): 1323-1334, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31068384
14.
Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy.
Cancer Res
; 66(12): 6421-31, 2006 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16778221
15.
Induction of neuregulin signaling in mouse schwann cells in vivo mimics responses to denervation.
J Neurosci
; 26(25): 6873-84, 2006 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16793894
16.
Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors.
Cancer Res
; 64(24): 9002-11, 2004 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15604265
17.
Functional microarray analysis of mammary organogenesis reveals a developmental role in adaptive thermogenesis.
Mol Endocrinol
; 16(6): 1185-203, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12040007
18.
Persistent parity-induced changes in growth factors, TGF-beta3, and differentiation in the rodent mammary gland.
Mol Endocrinol
; 16(9): 2034-51, 2002 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12198241
19.
Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit.
Cancer Discov
; 4(4): 452-65, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24444711
20.
Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers.
PLoS One
; 8(2): e54873, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23393560