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1.
Health Phys ; 93(5 Suppl): S165-73, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18049245

RESUMO

The Radiation Protection Group at the Los Alamos National Laboratory has a wind tunnel capable of measuring the aerosol collection efficiencies of air sampling devices. In the fall of 2005, the group received an internal Los Alamos request to perform aerosol collection efficiency tests on two air samplers manufactured by the Bladewerx Corporation (Rio Rancho, NM). This paper presents the results from tests performed in the wind tunnel facility at a test velocity of 0.5 m s. The SabreAlert (Portable Workplace Monitor) and the SabreBZM (Breathing Zone Monitor) are both designed to detect and measure the presence of alpha emitting isotopes in atmospheres. The SabreAlert was operated at two test air flow rates of 6 and 45 liters per minute (LPM), and the SabreBZM was operated at two test air flow rates of 3 and 19 LPM. The aerosol collection efficiencies of both samplers were evaluated with oleic acid (monodisperse) liquid droplet aerosols tagged with sodium fluorescein tracer. These test aerosols varied in size from about 2.3 to 17.2 microns (aerodynamic equivalent diameter). The SabreAlert was roughly 100% efficient in aerosol collection at a flow rate of 6 LPM, and had an aerodynamic cutpoint diameter of 11.3 microns at the 45 LPM flow rate. The SabreBZM had an aerodynamic cutpoint diameter of 6.7 microns at the 3 LPM flow rate, but the SabreBZM aerosol collection efficiency never exceeded 13.6% at the 19 LPM test flow rate condition.


Assuntos
Aerossóis/análise , Poluentes Radioativos do Ar/análise , Testes Respiratórios/instrumentação , Exposição Ocupacional/análise , Monitoramento de Radiação/instrumentação , Testes Respiratórios/métodos , Desenho de Equipamento , Análise de Falha de Equipamento , Miniaturização , Monitoramento de Radiação/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
2.
Environ Toxicol Chem ; 36(12): 3376-3386, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-28722808

RESUMO

West Nile virus (WNV) is maintained cryptically primarily in avian (passerine) populations, where it is transmitted by Culex spp. mosquitoes. Mosquito-control measures currently include physical activities to reduce mosquito-breeding sites and the application of mosquito larvicides or aerosolized insecticides to kill adults (adulticides) when arboviral diseases such as WNV or Zika virus are detected in mosquito populations. Organochlorine, organophosphorus, carbamate, and pyrethroid insecticides are often used. Previous work suggests an effect of pyrethroids on the immune system in a variety of vertebrates. We examined the effects of exposure to aerosolized Permanone® 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at approximately 103 to 106 times potential environmental concentrations on the response of captive zebra finches (Taeniopygia guttata) to experimental challenge with WNV. Compared to vehicle control birds, WNV outcome was unchanged (65% of birds produced a viremia) in the "low" exposure (9.52 ± 3.13 mg/m3 standard deviation [SD] permethrin) group but reduced in the "high" exposure (mean 376.5 ± 27.9 mg/m3 SD permethrin) group (30% were viremic; p < 0.05). After clearing WNV infection, birds treated with Permanone regained less body mass than vehicle-treated birds (p < 0.001). The present study suggests that exposure to aerosolized Permanone insecticide at levels exceeding typical application rates has the potential to not change or to mildly enhance a bird's resistance to WNV. Environ Toxicol Chem 2017;36:3376-3386. Published 2017 Wiley Periodicals Inc. on behalf of SETAC. This article is a US government work and, as such, is in the public domain in the United States of America.


Assuntos
Doenças das Aves/virologia , Tentilhões/virologia , Inseticidas/toxicidade , Permetrina/toxicidade , Butóxido de Piperonila/toxicidade , Febre do Nilo Ocidental/veterinária , Vírus do Nilo Ocidental , Animais , Doenças das Aves/imunologia , Doenças das Aves/fisiopatologia , Suscetibilidade a Doenças , Controle de Mosquitos , Viremia/virologia , Febre do Nilo Ocidental/imunologia , Febre do Nilo Ocidental/fisiopatologia , Febre do Nilo Ocidental/virologia , Zika virus
3.
Health Phys ; 110(5 Suppl 2): S59-66, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27023152

RESUMO

A portable instrument was developed to determine filter clogging and container leakage of in-place nuclear material storage canisters. This paper describes the development of an in-place filter tester for determining the "as found" condition of unopened canisters. The U.S. Department of Energy uses several thousand canisters for nuclear material storage, and air filters in the canister lids allow gases to escape while maintaining an equilibrated pressure without release of radioactive contamination. Diagnosing the filter condition and canister integrity is important for ensuring worker and public safety. Customized canister interfaces were developed for suction clamping (during tests) to two of the canister types in use at Los Alamos National Laboratory. Experimental leakage scenarios included: O-rings fouled with dust, cracked O-rings, and loose canister lids. The prototype tester has a measurement range for air leakage rates from 8.2 × 10 mL s up to 3.0 × 10 mL s. This is sufficient to measure a leak rate of 3.4 × 10 mL s, which is the Los Alamos helium leak criterion for post-drop tested canisters. The In-Place-Filter-Tester cannot measure to the lower value of the helium leak criterion for pre-drop tested canisters (1.0 × 10 mL s). However, helium leak testing requires canister disassembly, while the new in-place filter tester is able to assess the assembled condition of as-found and in-situ canisters.


Assuntos
Filtração/instrumentação , Filtração/normas , Exposição Ocupacional/prevenção & controle , Proteção Radiológica/normas , Humanos
4.
Health Phys ; 111(5): 442-50, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27682903

RESUMO

Evaluation of continuous air monitors in the presence of a plutonium aerosol is time intensive, expensive, and requires a specialized facility. The Radiation Protection Services Group at Los Alamos National Laboratory has designed a Dynamic Radioactive Source, intended to replace plutonium aerosol challenge testing. The Dynamic Radioactive Source is small enough to be inserted into the sampler filter chamber of a typical continuous air monitor. Time-dependent radioactivity is introduced from electroplated sources for real-time testing of a continuous air monitor where a mechanical wristwatch motor rotates a mask above an alpha-emitting electroplated disk source. The mask is attached to the watch's minute hand, and as it rotates, more of the underlying source is revealed. The measured alpha activity increases with time, simulating the arrival of airborne radioactive particulates at the air sampler inlet. The Dynamic Radioactive Source allows the temporal behavior of puff and chronic release conditions to be mimicked without the need for radioactive aerosols. The new system is configurable to different continuous air monitor designs and provides an in-house testing capability (benchtop compatible). It is a repeatable and reusable system and does not contaminate the tested air monitor. Test benefits include direct user control, realistic (plutonium) aerosol spectra, and iterative development of continuous air monitor alarm algorithms. Data obtained using the Dynamic Radioactive Source has been used to elucidate alarm algorithms and to compare the response time of two commercial continuous air monitors.


Assuntos
Poluentes Radioativos do Ar/análise , Poluição do Ar em Ambientes Fechados/análise , Plutônio/análise , Monitoramento de Radiação/instrumentação , Radioisótopos/isolamento & purificação , Ultrafiltração/instrumentação , Aerossóis/análise , Aerossóis/química , Poluentes Radioativos do Ar/química , Desenho de Equipamento , Análise de Falha de Equipamento/métodos , Plutônio/química , Monitoramento de Radiação/métodos , Radioisótopos/química , Radioisótopos/normas , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
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