Detalhe da pesquisa
1.
Charting the sequence-activity landscape of peptide inhibitors of translation termination.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33674389
2.
Labeling of a mutant estrogen receptor with an Affimer in a breast cancer cell line.
Biophys J
; 121(19): 3651-3662, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778844
3.
Recent structural advances in constrained helical peptides.
Med Res Rev
; 39(2): 749-770, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30307621
4.
Time-Gated Luminescence Detection of Enzymatically Produced Hydrogen Sulfide: Design, Synthesis, and Application of a Lanthanide-Based Probe.
Inorg Chem
; 57(2): 681-688, 2018 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29281273
5.
A "cross-stitched" peptide with improved helicity and proteolytic stability.
Org Biomol Chem
; 16(20): 3702-3706, 2018 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29725689
6.
Time-Gated Detection of Cystathionine γ-Lyase Activity and Inhibition with a Selective, Luminogenic Hydrogen Sulfide Sensor.
Chemistry
; 23(4): 752-756, 2017 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27734530
7.
Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.
Angew Chem Int Ed Engl
; 55(13): 4252-5, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26928945
8.
Antiviral atropisomers: conformational energy surfaces by NMR for host-directed myxovirus blockers.
J Chem Inf Model
; 54(8): 2214-23, 2014 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25058809
9.
Peptide-Drug Conjugates: An Emerging Direction for the Next Generation of Peptide Therapeutics.
J Med Chem
; 67(3): 1641-1661, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38277480
10.
Asymmetric synthesis of host-directed inhibitors of myxoviruses.
Beilstein J Org Chem
; 9: 197-203, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23400228
11.
Mapping the energy landscape of PROTAC-mediated protein-protein interactions.
Comput Struct Biotechnol J
; 21: 1885-1892, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923472
12.
Structure-Activity Relationships of the Antimicrobial Peptide Natural Product Apidaecin.
J Med Chem
; 66(17): 11831-11842, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603874
13.
Detection of thermal shift in cellular Keap1 by protein-protein interaction inhibitors using immunoblot- and fluorescence microplate-based assays.
STAR Protoc
; 3(2): 101265, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35391936
14.
An Innovation 10 Years in the Making: The Stories in the Pages of ACS Medicinal Chemistry Letters.
ACS Med Chem Lett
; 13(4): 540-545, 2022 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35450346
15.
The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf2.
iScience
; 25(1): 103703, 2022 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35036882
16.
Synthesis, Optimization, and Structure-Activity Relationships of Imidazo[1,2-a]pyrimidines as Inhibitors of Group 2 Influenza A Viruses.
J Med Chem
; 65(20): 14104-14120, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36260129
17.
A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ.
mBio
; 12(2)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33688014
18.
A recombinant Cedar virus based high-throughput screening assay for henipavirus antiviral discovery.
Antiviral Res
; 193: 105084, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34077807
19.
Molecular basis for the disruption of Keap1-Nrf2 interaction via Hinge & Latch mechanism.
Commun Biol
; 4(1): 576, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33990683
20.
Probing the topological tolerance of multimeric protein interactions: evaluation of an estrogen/synthetic ligand for FK506 binding protein conjugate.
Bioconjug Chem
; 21(10): 1880-9, 2010 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20919698