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1.
Nano Lett ; 22(1): 128-134, 2022 Jan 12.
Artigo em Inglês | MEDLINE | ID: mdl-34898223

RESUMO

When confined in circular cavities, graphene relativistic charge carriers occupy whispering gallery modes (WGMs) in analogy to classical acoustic and optical fields. The rich geometrical patterns of the WGMs decorating the local density of states offer promising perspectives to devise new disruptive quantum devices. However, exploiting these highly sensitive resonances requires the transduction of the WGMs to the outside world through source and drain electrodes, a yet unreported configuration. Here, we create a circular p-n island in a graphene device using a polarized scanning gate microscope tip and probe the resulting WGM signatures in in-plane electronic transport through the p-n island. Combining tight-binding simulations and the exact solution of the Dirac equation, we assign the measured device conductance features to WGMs and demonstrate mode selectivity by displacing the p-n island with respect to a constriction. This work therefore constitutes a proof of concept for graphene whisperitronic devices.

2.
BMC Public Health ; 21(1): 229, 2021 01 28.
Artigo em Inglês | MEDLINE | ID: mdl-33509155

RESUMO

BACKGROUND: Worldwide, most adolescent girls do not meet physical activity (PA) recommendations and very few PA programs are tailored specifically towards them. Even fewer information exists about the long-term effects of such programs. Some Canadian schools have implemented the FitSpirit PA intervention designed specifically for girls aged 12 to 17 years old. This paper describes the protocol of a quasi-experimental study evaluating long-term changes in health behaviours and outcomes following FitSpirit participation. METHODS: The study is conducted among schools that partner with FitSpirit every year. It started in 2018 and will be completed in 2022. The intervention comprises motivational talks, a turnkey running program, PA sessions and special events. Study participants fill out an online questionnaire twice a year. Follow-up questionnaires are sent at the end of each school year to the study participants who dropout from FitSpirit. The main outcome, changes in PA levels, is evaluated using questions validated for adolescents. Secondary outcomes are health (perceived health); lifestyle habits (sedentary activities, eating and sleeping habits); psychosocial outcomes (physical self-efficacy and body satisfaction); and FitSpirit appreciation (activity participation and satisfaction). Most questions originate from questionnaires validated for the adolescent population. Cross-sectional and longitudinal analyses will be performed. DISCUSSION: This study will provide one of the first longitudinal reports on the impact of a large extra-curricular PA intervention designed specifically for adolescent girls. The current study will uniquely contribute to PA research by assessing outcomes additional to PA levels, including markers of health, lifestyle habits and psychosocial determinants. TRIAL REGISTRATION: NCT, NCT03804151 , Registered on January 22, 2019; retrospectively registered.


Assuntos
Exercício Físico , Instituições Acadêmicas , Adolescente , Canadá , Criança , Estudos Transversais , Feminino , Humanos , Estilo de Vida , Serviços de Saúde Escolar
3.
Cult Med Psychiatry ; 44(1): 56-79, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-31214902

RESUMO

This study aimed to analyze main groups accused on social media of causing or spreading the 2014-2016 Ebola epidemic in West Africa. In this analysis, blame is construed as a vehicle of meaning through which the lay public makes sense of an epidemic, and through which certain classes of people become "figures of blame". Data was collected from Twitter and Facebook using key word extraction, then categorized thematically. Our findings indicate an overall proximate blame tendency: blame was typically cast on "near-by" figures, namely national governments, and less so on "distant" figures, such as generalized figures of otherness ("Africans", global health authorities, global elites). Our results also suggest an evolution of online blame. In the early stage of the epidemic, blame directed at the affected populations was more prominent. However, during the peak of the outbreak, the increasingly perceived threat of inter-continental spread was accompanied by a progressively proximal blame tendency, directed at figures with whom the social media users had pre-existing biopolitical frustrations. Our study proposes that pro-active and on-going analysis of blame circulating in social media can usefully help to guide communications strategies, making them more responsive to public perceptions.


Assuntos
Comunicação , Epidemias , Conhecimentos, Atitudes e Prática em Saúde , Doença pelo Vírus Ebola , Mídias Sociais , Humanos , Pesquisa Qualitativa
4.
J Clin Psychol ; 71(10): 1042-8, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26275066

RESUMO

OBJECTIVE: Trends indicate that clinical psychologists' theoretical orientations have changed over the last decades in North America, but research on this topic in Canada is scarce. We analyzed the orientation of psychologists over the last 20 years in the province of Quebec, where 46% of Canadian psychologists are located. METHOD: Data were collected annually through the board registration form of Quebec psychologists' professional order from 1993 to 2013. Univariate statistical analyses were realized on aggregated data. RESULTS: In 20 years, the proportion of clinicians choosing cognitive-behavioral therapy (CBT) as their main orientation grew from 18.4% to 38%, while preference for other orientations slightly declined. Existential-humanistic and psychodynamic-psychoanalytic approaches remained the primary orientation for around 21.7% and 21.5%, respectively. In 2013 (N = 8608), when taking into account 2 choices of theoretical orientation, 55.8% of clinicians chose CBT, 34.3% existential-humanistic orientation, 27.9% psychodynamic-analytic theories, and 21.8% systemic-interactional orientation. CONCLUSIONS: Findings underline trends in Quebec clinical practice characterized by an increase in the number of psychologists identifying cognitive-behavioral approach as their primary self-reported theoretical orientation.


Assuntos
Terapia Cognitivo-Comportamental/estatística & dados numéricos , Terapia Psicanalítica/estatística & dados numéricos , Teoria Psicológica , Psicologia Clínica/estatística & dados numéricos , Psicoterapia Psicodinâmica/estatística & dados numéricos , Terapia Cognitivo-Comportamental/tendências , Humanos , Terapia Psicanalítica/tendências , Psicologia Clínica/tendências , Psicoterapia Psicodinâmica/tendências , Quebeque
5.
Public Underst Sci ; 24(2): 225-40, 2015 02.
Artigo em Inglês | MEDLINE | ID: mdl-23942830

RESUMO

During the H1N1 pandemic, governments tailored their communications plans in order to influence risk perception and promote public compliance with the public health plan measures. Considering the volume and the content of calls to flu information centres as indicators of the public risk perception, this mixed method study compares the relation between public communications, risk perception and immunization behaviour in Quebec and France. Results suggest that advocating for clear information and coordination between health authorities and the media promotes adherence to preventive behaviour. However, over-exaggerating the risks and minimizing the population's agency may undermine health authority credibility.


Assuntos
Comportamentos Relacionados com a Saúde , Imunização/estatística & dados numéricos , Influenza Humana/psicologia , Disseminação de Informação/métodos , Meios de Comunicação de Massa , Percepção , França , Humanos , Vírus da Influenza A Subtipo H1N1/fisiologia , Quebeque , Medição de Risco
6.
Soc Sci Med ; 327: 115948, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-37216825

RESUMO

Exercise addiction has sparked a growing interest in the scientific and clinical literature, yet this behavioral addiction has mainly been investigated quantitatively, from a positivistic perspective. This article explores the subjective and embodied dimensions of exercise addiction, broadening current conceptions of this emerging, still unofficial mental health category. Building on carnal sociology, and through a thematic analysis of mobile interviews conducted with 17 self-proclaimed "exercise addicts" from Canada, this article examines the interrelations between the embodiment of exercise addiction and the normative social elements at stake in the shaping of the category, providing insights on how exercise is experienced as an addiction. Results show that most participants describe this addiction as "soft" and "positive", highlighting the virtues of exercising. However, their bodily accounts also reveal a suffering body, bringing forth the vices related to excessive exercising. Participants also put in relation the quantifiable and the sensible body, revealing the porous boundaries of this construct: exercise addiction can sometimes be regulatory in certain contexts and counternormative in others. Thus, it appears that "exercise addicts" enact various contemporary normative requirements, which vary from asceticism and body-ideals but also to the phenomenon of social and temporal acceleration. We argue that exercise addiction questions how certain behaviors, deemed potentially problematic, illustrate the tensions and complex articulations between embodying and resisting social normativity.


Assuntos
Comportamento Aditivo , Humanos , Exercício Físico , Canadá
7.
J Clin Med ; 11(5)2022 Feb 22.
Artigo em Inglês | MEDLINE | ID: mdl-35268247

RESUMO

A growing number of studies have used virtual reality (VR) for the assessment and treatment of body image disturbances (BIDs). This study, conducted in a community sample of adolescents, documents the convergent and discriminant validity between (a) the traditional paper-based Figure Rating Scale (paper-based FRS), (b) the VR-based Body Rating Scale (eLoriCorps-IBRS 1.1), and (c) the mobile app-based Body Rating Scale (eLoriCorps-IBRS 1.1-Mobile). A total of 93 adolescents (14 to 18 years old) participated in the study. Body dissatisfaction and body distortion were assessed through the paper-based FRS, the eLoriCorps-IBRS 1.1 and the eLoriCorps-IBRS 1.1-Mobile. Eating disorder symptoms, body image avoidance, and social physique anxiety were also measured. Correlation analyses were performed. Overall, the results showed a good and statistically significant convergence between allocentric perspectives as measured by the paper-based FRS, the eLoriCorps-IBRS 1.1 and the eLoriCorps-IBRS 1.1-Mobile. As expected, the egocentric perspective measured in VR produced different results from the allocentric perspective, and from cognitive-attitudinal-affective dimensions of BIDs, with the exception of body distortion. These differences support the discriminant validity of the egocentric perspective of eLoriCorps-IBRS 1.1 and are consistent with emerging evidence, highlighting a difference between experiencing the body from an egocentric (i.e., the body as a subject) and allocentric (i.e., the body as an object) perspective. The egocentric perspective could reflect a perceptual-sensory-affective construction of BIDs, whereas allocentric measures seem to be more related to a cognitive-affective-attitudinal construction of BIDs. Moreover, the results support the validity of the eLoriCorps-IBRS 1.1-Mobile with promising perspectives of implementation among young populations.

8.
Am J Public Health ; 101(5): 909-15, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-20724695

RESUMO

OBJECTIVES: We compared the evolution of perception of discrimination from 1998 to 2007 among recent Arab (Muslim and non-Muslim) and Haitian immigrants to Montreal; we also studied the association between perception of discrimination and psychological distress in 1998 and 2007. METHODS: We conducted this cross-sectional comparative research with 2 samples: one recruited in 1998 (n = 784) and the other in 2007 (n = 432). The samples were randomly extracted from the registry of the Ministry of Immigration and Cultural Communities of Quebec. Psychological distress was measured with the Hopkins Symptom Checklist-25. RESULTS: The perception of discrimination increased from 1998 to 2007 among the Arab Muslim, Arab non-Muslim, and Haitian groups. Muslim Arabs experienced a significant increase in psychological distress associated with discrimination from 1998 to 2007. CONCLUSIONS: These results confirm an increase in perception of discrimination and psychological distress among Arab Muslim recent immigrant communities after September 11, 2001, and highlight the importance this context may have for other immigrant groups.


Assuntos
Emigrantes e Imigrantes/psicologia , Preconceito , Ataques Terroristas de 11 de Setembro/psicologia , Estresse Psicológico/etiologia , Adulto , Árabes/psicologia , Lista de Checagem , Distribuição de Qui-Quadrado , Estudos Transversais , Emigrantes e Imigrantes/estatística & dados numéricos , Feminino , Haiti/etnologia , Humanos , Islamismo/psicologia , Masculino , Quebeque/epidemiologia , Análise de Regressão , Ataques Terroristas de 11 de Setembro/estatística & dados numéricos , Fatores Socioeconômicos , Estresse Psicológico/epidemiologia , Fatores de Tempo
9.
J Mater Sci Mater Med ; 22(3): 671-82, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21287241

RESUMO

Surface properties of nanoparticles to be used for radioimmunotherapy need to be optimized to allow antibody conjugation while ensuring biocompatibility. We aimed to investigate cell adhesion and proliferation onto different coatings to be used for nanoparticles. C, CH(x) or SiO(x) coatings deposited onto glass coverslips by magnetron deposition as well as nitrogen functionalized materials synthetized using different reactive sputtering conditions and PPAA (plasma polymerized allylamine) coating, were compared. Amine functionalization did increase hydrophilicity in all the materials tested. Biocompatibility was assessed by measuring cell viability, morphology, attachment, spreading, and pro-inflammatory cytokine secretion. The results show that C and CN(x) were the most biocompatible substrates while SiO(x) and SiO(x)N(y) were the most toxic materials. PPAA coatings displayed unexpectedly an intermediate biocompatibility. A correlation could be observed between wettability and cell proliferation except for C coated surface, indicating that more complex processes than hydrophilicity alone are taking place that affect cell functions.


Assuntos
Alilamina/química , Aminas/química , Anticorpos/química , Materiais Biocompatíveis/química , Adesão Celular , Sobrevivência Celular , Materiais Revestidos Biocompatíveis/química , Citocinas/metabolismo , Células Endoteliais/citologia , Vidro , Humanos , Inflamação , Nanopartículas/química , Nanotecnologia/métodos , Radioimunoterapia/métodos , Propriedades de Superfície
10.
Int J Yoga Therap ; 30(1): 103-109, 2020 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-32298142

RESUMO

The purpose of this article is to explore how the social work discipline could provide a complementary lens through which yoga therapy can be analyzed and evaluated by engaging in knowledge-creation practices and procedures that prioritize the "epistemic responsibility" described by philosopher Lorraine Code. More specifically, by seeking to strategically include often-subjugated types of knowledge and by focusing on redistributing epistemic power to agents that typically have been excluded from epistemic participation in contemporary yoga therapy research, the social work discipline, with its strong commitment to social justice, has the potential to contribute to filling an important gap in scientific literature. We begin by presenting the relevance of the social work perspective in relation to the field of yoga therapy. We next offer a reserved critical analysis of the dominant technical knowledge base that currently informs yoga therapy practice. This analysis highlights the social parameters that may be rendered invisible or left aside when adopting a positivist epistemological lens and justifies how the conceptual apparatus of epistemic responsibility serves as a potential platform for rethinking social work's position and future contributions to the field of yoga therapy. Finally, we mobilize the concept of cultural appropriation to illustrate how striving for epistemic responsibility provides an entry point for addressing the multilevel, complex social processes embedded in yoga therapy practice and research while aiming to capture the many voices-and hence the various truths-implicated in a democratic, reflexive, and inclusive research process.


Assuntos
Serviço Social , Yoga , Humanos , Conhecimento , Orientação , Justiça Social
11.
Artigo em Inglês | MEDLINE | ID: mdl-32570878

RESUMO

Adolescence is a crucial time in the development and maintenance of lifestyle habits. Interventions to improve health-related behaviors are important, including those that can contribute to an increase in physical activity (PA). During adolescence, PA typically decreases with age, particularly in girls. The FitSpirit program offers services that help Canadian schools from Quebec and Ontario implement PA interventions for adolescent girls. This study aimed to evaluate changes in participants' PA levels and lifestyle habits (sedentary time, sleep duration and eating habits) and to assess whether these changes depended on adherence to the Canadian 24-Hour Movement Guidelines and Canada's Food Guide recommendations at enrollment. At the time of FitSpirit registration (between December 2018 and March 2019) and in May/June 2019, 73 participants answered online questionnaires. The participants reported improvements, with an increase in the number of days with PA and a decrease in daily consumption of sweets. The greatest changes were observed in those who did not adhere to the Canadian recommendations before enrollment and who significantly increased their number of days with PA and their consumption of fruits and vegetables, and decreased their screen time. In conclusion, participation in FitSpirit improved several health behaviors among adolescent girls, particularly those who did not comply with the Canadian recommendations at enrollment.


Assuntos
Exercício Físico , Comportamentos Relacionados com a Saúde , Estilo de Vida , Adolescente , Feminino , Hábitos , Humanos , Ontário , Quebeque
12.
J Nerv Ment Dis ; 197(9): 695-9, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19752650

RESUMO

This brief report illustrates how the migration context can affect specific item validity of mental health measures. The SCL-25 was administered to 432 recently settled immigrants (220 Haitian and 212 Arabs). We performed descriptive analyses, as well as Infit and Outfit statistics analyses using WINSTEPS Rasch Measurement Software based on Item Response Theory. The participants' comments about the item You feel everything requires a lot of effort in the SCL-25 were also qualitatively analyzed. Results revealed that the item You feel everything requires a lot of effort is an outlier and does not adjust in an expected and valid fashion with its cluster items, as it is over-endorsed by Haitian and Arab healthy participants. Our study thus shows that, in transcultural mental health research, the cultural and migratory contexts may interact and significantly influence the meaning of some symptom items and consequently, the validity of symptom scales.


Assuntos
Comparação Transcultural , Depressão/diagnóstico , Emigrantes e Imigrantes/psicologia , Etnicidade/psicologia , Inventário de Personalidade/estatística & dados numéricos , Adolescente , Adulto , Idoso , Árabes/psicologia , Árabes/estatística & dados numéricos , Canadá , Análise por Conglomerados , Emigrantes e Imigrantes/estatística & dados numéricos , Etnicidade/estatística & dados numéricos , Feminino , Haiti/etnologia , Nível de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Estatísticos , Psicometria , Reprodutibilidade dos Testes , Estresse Psicológico/diagnóstico , Estresse Psicológico/psicologia , Inquéritos e Questionários
13.
Health Place ; 15(3): 721-30, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19217820

RESUMO

Caribbean and Filipino immigrant families in Canada have much in common: the women have often immigrated as domestic workers, first-generation children may be separated from their parents for long periods, and they must deal with negative stereotypes of their ethnic group. This transcultural study looks at the associations between family relations and adolescents' perceptions of both their own group and the host society, and analyzes how these affect their mental health. The results suggest that family cohesion plays a key role in shaping adolescents' perceptions of racism in the host country and in promoting a positive appraisal of their own community, thus highlighting the need for a systemic understanding of family and intergroup relations.


Assuntos
Atitude , Relações Familiares , Preconceito , Instituições Acadêmicas , Aculturação , Adolescente , Adulto , Canadá , Criança , Coleta de Dados , Emigrantes e Imigrantes/psicologia , Feminino , Grupos Focais , Humanos , Masculino , Pessoa de Meia-Idade , Filipinas/etnologia , Índias Ocidentais/etnologia
14.
Sante Ment Que ; 34(1): 127-42, 2009.
Artigo em Francês | MEDLINE | ID: mdl-19475197

RESUMO

This article describes a collaborative mental health care project for youths, implemented in Montreal in a multiethnic setting. The authors examine the adjustments needed in the shared-care model to address the complexity of cultural and cooperation issues raised in the provision of services to a multiethnic population. A preliminary qualitative evaluation of the project shows how first-line workers face many uncertainties, stemming from both the institutional context and the multicultural reality of the population served. Results from this study advance the hypothesis that although uncertainties may generate discomfort and confusion, they may also open a space for innovation and acceptance of otherness.


Assuntos
Serviços de Saúde do Adolescente/organização & administração , Serviços de Saúde Mental/organização & administração , Adolescente , Diversidade Cultural , Humanos , Relações Interpessoais , Quebeque
15.
Public Underst Sci ; 28(8): 932-948, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31434548

RESUMO

Since its initial publication, the Diagnostic and Statistical Manual of Mental Disorders has been the object of criticism which has led to regular revisions by the American Psychiatric Association. This article analyses the debates that surrounded the publication of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.). Building on the concepts of public arenas and reception theory, it explores the meaning encoded in the manual by audiences. Our results, which draw from a thematic analysis of traditional and digital media sources, identify eight audiences that react to the American Psychiatric Association's narrative of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.): conformist, reformist, humanist, culturalist, naturalist, conflictual, constructivist and utilitarian. While some of their claims present argumentative polarities, others overlap, thus challenging the idea, often presented in academic publications, of a fixed debate. In order to further discuss on the Diagnostic and Statistical Manual of Mental Disorders, we draw attention to claims that 'travel' across different communities of audiences.


Assuntos
Manual Diagnóstico e Estatístico de Transtornos Mentais , Guias como Assunto , Humanos
16.
Chem Res Toxicol ; 21(9): 1698-705, 2008 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-18636756

RESUMO

Experimental studies indicate that carbon nanotubes (CNTs) have the potential to induce adverse pulmonary effects, including alveolitis, fibrosis, and genotoxicity in epithelial cells. Here, we explored the physicochemical determinants of these toxic responses with progressively and selectively modified CNTs: ground multiwall CNTs modified by heating at 600 degrees C (loss of oxygenated carbon functionalities and reduction of oxidized metals) or at 2400 degrees C (annealing of structural defects and elimination of metals) and by grinding the material that had been heated at 2400 degrees C before (introduction of structural defects in a metal-deprived framework). The CNTs were administered intratracheally (2 mg/rat) to Wistar rats to evaluate the short-term response (3 days) in bronchoalveolar lavage fluid (LDH, proteins, cellular infiltration, IL-1beta, and TNF-alpha). The long-term (60 days) lung response was assessed biochemically by measuring the lung hydroxyproline content and histologically. In vitro experiments were also performed on rat lung epithelial cells to assess the genotoxic potential of the modified CNTs with the cytokinesis block micronucleus assay. The results show that the acute pulmonary toxicity and the genotoxicity of CNT were reduced upon heating but restored upon grinding, indicating that the intrinsic toxicity of CNT is mainly mediated by the presence of defective sites in their carbon framework.


Assuntos
Pneumopatias/induzido quimicamente , Nanotubos de Carbono/toxicidade , Doença Aguda , Animais , Líquido da Lavagem Broncoalveolar/química , Células Cultivadas , Relação Dose-Resposta a Droga , Feminino , Injeções Espinhais , L-Lactato Desidrogenase/análise , Pneumopatias/patologia , Macrófagos/efeitos dos fármacos , Testes para Micronúcleos , Nanotubos de Carbono/química , Neutrófilos/efeitos dos fármacos , Proteínas/análise , Ratos , Ratos Wistar
17.
Shock ; 49(4): 385-392, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-28930918

RESUMO

The neutrophil-to-lymphocyte ratio (NLR) is an inflammation score recognized as associated with outcome. Although inflammation has been shown to correlate with the development of acute-on-chronic liver failure (ACLF), we sought to investigate the role of NLR in predicting 90-day mortality in cirrhotic patients experiencing ACLF. We performed a retrospective cohort study involving a total of 108 consecutive cirrhotic patients admitted in the intensive care unit (ICU). NLR, clinical and biological data were recorded. Of the total, 75 patients had ACLF. The 90-day mortality rate was 53%. ACLF patients displayed higher NLR values in comparison with cirrhotic patients without ACLF throughout the ICU stay. NLR proved more elevated in nonsurvivors ACLF patients, with mortality correlating with increasing quartiles of NLR. On multivariable Cox regression analysis, NLR was found to be a predictor of mortality along with the Sequential Organ Failure Assessment (SOFA) score and mechanical ventilation requirement. The model for end-stage liver disease (MELD) score was not predictive of 90-days mortality. Performance analysis revealed an area under curve of 0.71 [95% confidence interval: 0.59-0.82] regarding NLR capacity to predict 90-days mortality. When including NLR, SOFA score, and mechanical ventilation requirement into the final model, the area under curve was significantly higher (0.81 [95% confidence interval: 0.72-0.91]).These findings suggest that NLR is associated with mortality in ACLF patients admitted to the ICU. Combining NLR, SOFA score, and the need for mechanical ventilation could be a useful prognostic tool to identify ACLF patients at a higher risk of mortality.


Assuntos
Insuficiência Hepática Crônica Agudizada/imunologia , Insuficiência Hepática Crônica Agudizada/mortalidade , Linfócitos/citologia , Neutrófilos/citologia , Insuficiência Hepática Crônica Agudizada/metabolismo , Idoso , Feminino , Humanos , Unidades de Terapia Intensiva/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
18.
Arch Gerontol Geriatr ; 60(2): 366-71, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25488015

RESUMO

BACKGROUND: The NLR is a prognostic factor for outcome and survival in cardiology, oncology and digestive surgery. NLR has not yet been studied in HF. METHODS: Retrospective analysis of a prospective cohort of 247 consecutive patients, older than 65 years, operated for HF. Mortality at 12 months was registered, as the perioperative NLR values. RESULTS: After hip surgery in the 247 patients (women 71%, median age 85 years, range: 66-102), the mortality was 27.2% [95%confidence interval (CI): 21.4-33.0] at 12 months. Univariate analysis detected four risk factors for mortality: age (Hazard Ratio (HR)--by 10 year-increments: 2.08 [95%CI: 1.37-3.17], P<0.001), male gender (HR: 1.92 [95%CI: 1.17-3.14], P=0.009, MCM (≥3) (HR: 1.71 [95%CI: 1.006-2.92], P=0.047 and NLR>5 at day 5 (HR: 1.8 [95%CI: 1.11-2.94], P=0.002). In multivariate analysis, two factors remained significantly associated with mortality: age (HR: 2.28 [95%CI: 1.49-3.47], P<0.001) and male gender (HR: 2.26 [95%CI: 1.38-3.72], P=0.001). Two independent risk factors of postoperative cardiovascular complications were identified: NLR>5 at day 5 (Odds Ratio (OR): 3.34 [95%CI: 2.33-4.80], P=0.001) and MCM (OR: 3.04 [95%CI: 2.16-4.29], P=0.006). A higher risk of infection was independently associated with a NLR>5 at day 5 (OR: 2.12 [95%CI: 1.44-3.11], P=0.02). CONCLUSIONS: The NLR at fifth postoperative day is a risk factor of postoperative mortality and cardiovascular complications.


Assuntos
Fraturas do Quadril/mortalidade , Fraturas do Quadril/cirurgia , Contagem de Leucócitos , Neutrófilos/metabolismo , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Bélgica/epidemiologia , Feminino , Fraturas do Quadril/sangue , Humanos , Masculino , Análise Multivariada , Período Pós-Operatório , Estudos Retrospectivos , Fatores de Risco , Fatores Sexuais
19.
Chem Commun (Camb) ; (6): 558-9, 2002 Mar 21.
Artigo em Inglês | MEDLINE | ID: mdl-12120122

RESUMO

Driving the equilibrium between selenides and osmium(VIII) reagents with selenoxides and osmium(VI) by a subsequent reaction (rearrangement of allyl selenoxides to allyl alcohols or addition of osmium(VIII) species on C=C double bonds) to one side, allows the transformation of methyl geranyl selenides to linalool and of methyl citronellyl selenoxide to 6,7-dihydroxy citronellyl selenide.

20.
Presse Med ; 33(12 Pt 1): 784-90, 2004 Jul 10.
Artigo em Francês | MEDLINE | ID: mdl-15343093

RESUMO

INTRODUCTION: A study on the relationship between the ANDEM--Agence Nationale pour le Développement de l'Evaluation Médicale (French agency for the development of health technology assessment) and the learned societies showed that a definition of the role of these organisations and criteria to define learned societies were lacking. We conducted a survey among the learned societies in the field of medicine so as to elaborate a definition. METHODS: We used the files of the learned societies of the Anaes--Agence Nationale d'Accréditation et d'Evaluation en Santé (French Agency for accreditation and evaluation in health) in 1998, which included 225 organisations. We sent a letter together with a single-page questionnaire and copies of the 2 publications on the relationship between the ANDEM and the learned societies. To analyse the suggestions for a definition, having read the replies, a segmentation of the population, the means and modalities of action and the aims and fields of action were used. A proposal for a definition was discussed during 2002/2003 with the board of the Fédération des Spécialités Médicales (FSM) (Federation of medical specialties) regrouping 33 medical and 12 surgical societies. Three meetings between a representative of the Anaes and the board of the FSM resulted in the proposition of so-called "validation" criteria for learned societies. A search on the French Internet listing such societies was made using a research motor (March 20, 2004). RESULTS: Out of the 225 organisations contacted, 129 (57%) replied. Among the latter, 115 considered themselves as a learned society and 14 did not. Among the 115 organisations defining themselves as a learned society, 97 proposed a definition, 16 made use of the definitions proposed in the questionnaire and 81 proposed their own definition. The analysis identified 6 important elements (reporting, knowledge, education, research, diffusion, promotion). The data analysed permitted the elaboration of a definition based on the proposals of the learned societies: "An organised group, within the framework of a given discipline, the members' aim of which is to report on their work, to improve knowledge on their discipline, to ensure education and research, to diffuse information on their work and research and to support and promote their discipline". Thirty-two of the 45 societies of the FSM accepted the 11 validation criteria proposed, some of which were commented on. Only one society abstained and 12 did not reply. No French Internet web site listing the learned societies specified a definition of criteria for inclusion in the lists. DISCUSSION: A definition of the learned societies and validation criteria, obtained through the participation of the principle actors, could serve as a basis for the recognition and identification of such societies.


Assuntos
Objetivos Organizacionais , Sociedades Médicas , Coleta de Dados , França , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Tecnologia/tendências
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