Monitoring the fetal heart rate variability during labor.

In respect to the main goal of our ongoing work for estimating the heart rate variability (HRV) from fetal electrocardiogram (FECG) signals for monitoring the health of the fetus, we investigate in this paper the possibility of extracting the fetal heart rate variability (HRV) directly from the abdominal composite recordings. Our proposed approach is based on a combination of two techniques: Periodic Component Analysis (PiCA) and recursive least square (RLS) adaptive filtering. The Fetal HRV of the estimated FECG signal is compared to a reference value extracted from an FECG signal recorded by using a spiral electrode attached directly to the fetal scalp. The results obtained show that the fetal HRV can be directly evaluated from the abdominal composite recordings without the need of recording an external reference signal.

Sensors' Ground Reaction Force behavior for both Normal and Parkinson subjects--A qualitative study.

Characterization of normal and abnormal Gait has been a major research field for decades, whether in fall prevention, sports biomechanics or even disease indication. In this paper, we assess time domain statistical properties of the Vertical Ground Reaction Force (VGRF) during moderate-pace walking, aiming eventually to create a reliable mathematical model of VGRF for normal and abnormal cases. For that endeavor, first order statistical analysis was performed upon signal segmentation in order to determine the degree of stationarity and base the model upon it. Furthermore, we performed curve fitting of the VGRF time series between present and past values, which led us to model the waveform with linear regression via Autoregressive Model for both Normal Walking Signals and Parkinson diseased patients' walking signals. However this is done only for one chosen sensor. However, it would be crucial to take the advantage of the array of sensors. Evaluating the cross-covariance between multi-sensor data of a given subject at different time lags capture the most important information. The seasonality in the values give a quite important indications of the behavior of data. The objective behind this analysis is to recommend a preliminary basis to create reliable mathematical model of normal walking signals versus pathological walking signals, that we will emphasize in a complementary work, in the simplest way available and creating fall prevention indicators for old patients.

Cross-correlation analysis of multichannel uterine EMG signals.

The prevention of preterm labor remains one of the primary goals of obstetric research. One way to achieve this goal effectively is to understand the mechanisms regulating the uterine contractility. Herein, we evaluate the correlation between uterine electrical activities recorded from spatially-distributed regions by calculating the nonlinear regression coefficient. Results have shown that, during pregnancy, the degree of interdependence between signals is very high whereas, at labor, the correlation between the signals decreases remarkably. We conclude that pregnancy is characterized by the presence of few local potential sources dominating the other sources while at the onset of labor, the number of these sources increases remarkably which affects therefore the correlation between the signals.

Detecting missing signals in multichannel recordings by using higher order statistics.

In real world applications, a multichannel acquisition system is susceptible of having one or many of its sensors displaced or detached, leading therefore to the loss or corruption of the recorded signals. In this paper, we present a technique for detecting missing or corrupted signals in multichannel recordings. Our approach is based on Higher Order Statistics (HOS) analysis. Our approach is tested on real uterine electromyogram (EMG) signals recorded by 4×4 electrode grid. Results have shown that HOS descriptors can discriminate between the two classes of signals (missing vs. non-missing). These results are supported by statistical analysis using the t-test which indicated good statistical significance of 95% confidence level.

Classification of multichannel uterine EMG signals.

Classification of multichannel uterine electromyogram (EMG) signals is addressed. Signals were recorded by a matrix of 16 electrodes. First, signals corresponding to each channel were individually classified using an artificial neural network (ANN) based on radial basis functions (RBF). The results have shown that the classification performance varies from one channel to another. Then, a decision fusion method based on these classification performances was tested. After fusion, the network yielded better classification accuracy than any individual channel could provide. The high percentage of correctly classified labor/non-labor events proves the efficiency of multichannel recordings in detecting labor. These findings can be very useful for the aim of classifying antepartum versus labor patients.

Classification performance of the frequency-related parameters derived from uterine EMG signals.

Frequency-related parameters derived from the uterine electromyogram (EMG) signals are widely used in many pregnancy monitoring and preterm delivery prediction studies. Although they are classical parameters, they are well suited for quantifying uterine EMG signals and have many advantages over amplitude-related parameters. The present work aims to compare various frequency-related parameters according to their classification performances (pregnancy vs. labor) using the receiver operating characteristic (ROC) curve analysis. The comparison between the parameters indicates that median frequency is the best frequency-related parameter that can be used for distinguishing between pregnancy and labor contractions. We conclude that median frequency can be the representative frequency-related parameter for classification problems of uterine EMG.

Complexity analysis of the uterine electromyography.

In respect to the main goal of our ongoing work for predicting preterm birth, we analyze in this paper the complexity of the uterine electromyography (EMG) by using the sample entropy (SampEn) algorithm. By considering recent methodological developments, we measure the SampEn over multiple scales using the wavelet packet decomposition method. The results obtained from the analyzed data indicate that SampEn decreases along pregnancy. Furthermore, we demonstrate that the computed SampEn parameter may discriminate between the two classes (pregnancy/labor). The results are supported by statistical analysis using t-test indicating good statistical significance with a confidence level of 95%. A surrogate data test is also performed to investigate the nature of the underlying dynamics of our experimental data. The results are very promising for monitoring pregnancy and detecting labor to help identify preterm labor.