Detalhe da pesquisa
1.
GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models.
Breast Cancer Res Treat
; 180(2): 359-368, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32030569
2.
The In Vitro Effects of Pentamidine Isethionate on Coagulation and Fibrinolysis.
Molecules
; 24(11)2019 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31174390
3.
Naringenin targets ERK2 and suppresses UVB-induced photoaging.
J Cell Mol Med
; 20(5): 909-19, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26861188
4.
Bile Acid Conjugated DNA Chimera that Conditionally Inhibits Carbonic Anhydrase-II in the Presence of MicroRNA-21.
Bioconjug Chem
; 26(8): 1606-12, 2015 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26191606
5.
Pentamidine analogs as inhibitors of [(3)H]MK-801 and [(3)H]ifenprodil binding to rat brain NMDA receptors.
Bioorg Med Chem
; 23(15): 4489-4500, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26117647
6.
Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents.
Molecules
; 20(3): 3898-941, 2015 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25738536
7.
New Triazole-Based Potent Inhibitors of Human Factor XIIa as Anticoagulants.
ACS Omega
; 9(9): 10694-10708, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38463342
8.
Triazol-1-yl Benzamides Promote Anticoagulant Activity via Inhibition of Factor XIIa.
Cardiovasc Hematol Agents Med Chem
; 21(2): 108-119, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36321236
9.
Sulphated penta-galloyl glucopyranoside (SPGG) is glycosaminoglycan mimetic allosteric inhibitor of cathepsin G.
RPS Pharm Pharmacol Rep
; 2(1): rqad001, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36844783
10.
Design, Synthesis, and Evaluation of Niclosamide Analogs as Therapeutic Agents for Enzalutamide-Resistant Prostate Cancer.
Pharmaceuticals (Basel)
; 16(5)2023 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242518
11.
Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs.
Carcinogenesis
; 33(2): 459-65, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22139441
12.
Ethacrynic acid is an inhibitor of human factor XIIIa.
BMC Pharmacol Toxicol
; 23(1): 35, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35642005
13.
Factor IX(a) inhibitors: an updated patent review (2003-present).
Expert Opin Ther Pat
; 32(4): 381-400, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-34991418
14.
Sulfonated non-saccharide molecules and human factor XIa: Enzyme inhibition and computational studies.
Chem Biol Drug Des
; 100(1): 64-79, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377529
15.
From Pure Antagonists to Pure Degraders of the Estrogen Receptor: Evolving Strategies for the Same Target.
ACS Omega
; 6(14): 9334-9343, 2021 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33869913
16.
Sulfonated Nonsaccharide Heparin Mimetics Are Potent and Noncompetitive Inhibitors of Human Neutrophil Elastase.
ACS Omega
; 6(19): 12699-12710, 2021 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34056422
17.
Discovery of Benzyl Tetraphosphonate Derivative as Inhibitor of Human Factor Xia.
ChemistryOpen
; 9(11): 1161-1172, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33204588
18.
Design, synthesis and evaluation of belinostat analogs as histone deacetylase inhibitors.
Future Med Chem
; 11(21): 2765-2778, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31702394
19.
ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models.
Oncotarget
; 9(6): 6924-6937, 2018 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467940
20.
Solvation of transmembrane proteins by isotropic membrane mimetics: a molecular dynamics study.
J Phys Chem B
; 111(38): 11285-96, 2007 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-17784746