Detalhe da pesquisa
1.
Identification of potential inhibitors of casein kinase 2 alpha of Plasmodium falciparum with potent in vitro activity.
Antimicrob Agents Chemother
; 67(11): e0058923, 2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37819090
2.
Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika.
J Chem Inf Model
; 62(24): 6825-6843, 2022 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239304
3.
Chalcones from Angelica keiskei (ashitaba) inhibit key Zika virus replication proteins.
Bioorg Chem
; 120: 105649, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35124513
4.
Tetracyclines, a promise for neuropsychiatric disorders: from adjunctive therapy to the discovery of new targets for rational drug design in psychiatry.
Behav Pharmacol
; 32(2&3): 123-141, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33595954
5.
Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors.
Bioorg Chem
; 109: 104719, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33636437
6.
Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32601162
7.
A Proline Derivative-Enriched Fraction from Sideroxylon obtusifolium Protects the Hippocampus from Intracerebroventricular Pilocarpine-Induced Injury Associated with Status Epilepticus in Mice.
Int J Mol Sci
; 21(11)2020 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32545390
8.
High Throughput and Computational Repurposing for Neglected Diseases.
Pharm Res
; 36(2): 27, 2018 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30560386
9.
Molecular dynamics simulations of Zika virus NS3 helicase: Insights into RNA binding site activity.
Biochem Biophys Res Commun
; 492(4): 643-651, 2017 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28341122
10.
CHARMM Force Field Parameterization of Peroxisome Proliferator-Activated Receptor γ Ligands.
Int J Mol Sci
; 18(1)2016 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28025495
11.
Correction for Ferreira et al., "Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax".
Antimicrob Agents Chemother
; 64(11)2020 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33082230
12.
Whole genome sequencing identifies novel mutations in malaria parasites resistant to artesunate (ATN) and to ATN + mefloquine combination.
Front Cell Infect Microbiol
; 14: 1353057, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38495651
13.
GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain.
J Biol Chem
; 287(33): 28169-79, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22584573
14.
Identification of novel Zika virus NS3 protease inhibitors with different inhibition modes by integrative experimental and computational approaches.
Biochimie
; 212: 143-152, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37088408
15.
The tetrapartite synapse in neuropsychiatric disorders: Matrix metalloproteinases (MMPs) as promising targets for treatment and rational drug design.
Biochimie
; 201: 79-99, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35931337
16.
Computational and Experimental Approaches Identify Beta-Blockers as Potential SARS-CoV-2 Spike Inhibitors.
ACS Omega
; 7(32): 27950-27958, 2022 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35983371
17.
Neuroprotective effects of dimethyl fumarate against depression-like behaviors via astrocytes and microglia modulation in mice: possible involvement of the HCAR2/Nrf2 signaling pathway.
Naunyn Schmiedebergs Arch Pharmacol
; 395(9): 1029-1045, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665831
18.
Natural Compounds as Non-Nucleoside Inhibitors of Zika Virus Polymerase through Integration of In Silico and In Vitro Approaches.
Pharmaceuticals (Basel)
; 15(12)2022 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36558945
19.
Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate.
Sci Rep
; 12(1): 10601, 2022 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35732685
20.
Repurposing of Tetracyclines for COVID-19 Neurological and Neuropsychiatric Manifestations: A Valid Option to Control SARS-CoV-2-Associated Neuroinflammation?
J Neuroimmune Pharmacol
; 16(2): 213-218, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33534108